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Vilaplana, FranciscoORCID iD iconorcid.org/0000-0003-3572-7798
Alternative names
Publications (10 of 86) Show all publications
Ramos, M., Burgos, N., Barnard, A., Evans, G., Preece, J., Graz, M., . . . Jimenez, A. (2019). Agaricus bisporus and its by-products as a source of valuable extracts and bioactive compounds. Food Chemistry, 292, 176-187
Open this publication in new window or tab >>Agaricus bisporus and its by-products as a source of valuable extracts and bioactive compounds
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2019 (English)In: Food Chemistry, ISSN 0308-8146, E-ISSN 1873-7072, Vol. 292, p. 176-187Article, review/survey (Refereed) Published
Abstract [en]

Edible mushrooms constitute an appreciated nutritional source for humans due to their low caloric intake and their high content in carbohydrates, proteins, dietary fibre, phenolic compounds, polyunsaturated fatty acids, vitamins and minerals. It has been also demonstrated that mushrooms have health-promoting benefits. Cultivation of mushrooms, especially of the most common species Agaricus bisporus, represents an increasingly important food industry in Europe, but with a direct consequence in the increasing amount of by-products from their industrial production. This review focuses on collecting and critically investigating the current data on the bioactive properties of Agaricus bisporus as well as the recent research for the extraction of valuable functional molecules from this species and its by-products obtained after industrial processing. The state of the art regarding the antimicrobial, antioxidant, anti-allergenic and dietary compounds will be discussed for novel applications such as nutraceuticals, additives for food or cleaning products.

Place, publisher, year, edition, pages
ELSEVIER SCI LTD, 2019
Keywords
Agaricus Bisporus, By-products, Valorisation, Extraction techniques, Bioactive compounds
National Category
Food Science
Identifiers
urn:nbn:se:kth:diva-252359 (URN)10.1016/j.foodchem.2019.04.035 (DOI)000466346600025 ()31054663 (PubMedID)2-s2.0-85064443482 (Scopus ID)
Note

QC 20190724

Available from: 2019-07-24 Created: 2019-07-24 Last updated: 2019-07-24Bibliographically approved
Menzel, C., Gonzalez-Martinez, C., Chiralt, A. & Vilaplana, F. (2019). Antioxidant starch films containing sunflower hull extracts. Carbohydrate Polymers, 214, 142-151
Open this publication in new window or tab >>Antioxidant starch films containing sunflower hull extracts
2019 (English)In: Carbohydrate Polymers, ISSN 0144-8617, E-ISSN 1879-1344, Vol. 214, p. 142-151Article in journal (Refereed) Published
Abstract [en]

This study explores the preparation of antioxidant starch food packaging materials by the incorporation of valuable phenolic compounds extracted from sunflower hulls, which are an abundant by-product from food industry. The phenolic compounds were extracted with aqueous methanol and embedded into starch films. Their effect on starch films was investigated in terms of antioxidant activity, optical, thermal, mechanical, barrier properties and changes in starch molecular structure. The starch molecular structure was affected during thermal processing resulting in a decrease in molar mass, smaller amylopectin molecules and shorter amylose branches. Already 1-2% of extracts were sufficient to produce starch films with high antioxidant capacity. Higher amounts (4-6%) of extract showed the highest antioxidant activity, the lowest oxygen permeability and high stiffness and poor extensibility. The phenolic extracts affected predominantly the mechanical properties, whereas other changes could mainly be correlated to the lower glycerol content which was partially substituted by the extract.

Place, publisher, year, edition, pages
Elsevier, 2019
Keywords
Renewable packaging, Physical properties, Antimicrobial activity, Molecular weight, DPPH, Chlorogenic acid
National Category
Polymer Technologies
Identifiers
urn:nbn:se:kth:diva-249838 (URN)10.1016/j.carbpol.2019.03.022 (DOI)000462586900017 ()2-s2.0-85062949959 (Scopus ID)
Note

QC 20190426

Available from: 2019-04-26 Created: 2019-04-26 Last updated: 2019-04-26Bibliographically approved
Berglund, J., Chen, P., Vilaplana, F. & Wohlert, J. (2019). Computer modeling of the structure and dynamics of hemicelluloses. Paper presented at National Meeting of the American-Chemical-Society (ACS), MAR 31-APR 04, 2019, Orlando, FL. Abstracts of Papers of the American Chemical Society, 257
Open this publication in new window or tab >>Computer modeling of the structure and dynamics of hemicelluloses
2019 (English)In: Abstracts of Papers of the American Chemical Society, ISSN 0065-7727, Vol. 257Article in journal, Meeting abstract (Other academic) Published
Place, publisher, year, edition, pages
AMER CHEMICAL SOC, 2019
National Category
Paper, Pulp and Fiber Technology
Identifiers
urn:nbn:se:kth:diva-257594 (URN)000478860502443 ()
Conference
National Meeting of the American-Chemical-Society (ACS), MAR 31-APR 04, 2019, Orlando, FL
Note

QC 20190919

Available from: 2019-09-19 Created: 2019-09-19 Last updated: 2019-10-15Bibliographically approved
Farahani, S. K., Escalante, A., Toriz, G., Vilaplana, F., Gatenholm, P., Hansson, P. & Wågberg, L. (2019). Experimental and Theoretical Evaluation of the Solubility/Insolubility Spruce Xylan (Arabino Glucuronoxylan). Biomacromolecules, 20(3), 1263-1270
Open this publication in new window or tab >>Experimental and Theoretical Evaluation of the Solubility/Insolubility Spruce Xylan (Arabino Glucuronoxylan)
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2019 (English)In: Biomacromolecules, ISSN 1525-7797, E-ISSN 1526-4602, Vol. 20, no 3, p. 1263-1270Article in journal (Refereed) Published
Abstract [en]

The molecular solubility of softwood arabinoglucuronoxylan (AGX) has been thoroughly investigated, and it has been shown that the chemical and physical structures of the extracted hemicellulose are not significantly influenced by different purification steps, but a transient molecular solubility of AGX was observed in aqueous media at low concentrations (1 g/L) when the dissolved macromolecules had a hydrodynamic diameter of up to 10 nm. A phase separation was detected when the concentration was increased to 15 g/L leading to an association of the smaller molecules into fractal structures with a considerably larger diameter, even though the dispersions were still transparent to ocular inspection. Dynamic Light Scattering and Cryo-Transmission Electron Microscopy showed dimensions in the range of 1000 nm. The phase separation of the sample was further characterized by estimating the χ-interaction parameter of AGX in water using the Flory-Huggins theory, and the results supported that water is a poor solvent for AGX. This behavior is crucial when films and hydrogels based on these biopolymers are made, since the association will dramatically affect barrier and mechanical properties of films made from these materials.

Place, publisher, year, edition, pages
American Chemical Society (ACS), 2019
National Category
Physical Chemistry
Identifiers
urn:nbn:se:kth:diva-248093 (URN)10.1021/acs.biomac.8b01686 (DOI)000461270500013 ()30689362 (PubMedID)2-s2.0-85061537168 (Scopus ID)
Note

QC 20190429

Available from: 2019-04-29 Created: 2019-04-29 Last updated: 2019-05-22Bibliographically approved
Rudjito, R. C., Ruthes, A. C., Jimenez-Quero, A. & Vilaplana, F. (2019). Feruloylated Arabinoxylans from Wheat Bran: Optimization of Extraction Process and Validation at Pilot Scale. ACS Sustainable Chemistry and Engineering, 7(15), 13167-13177
Open this publication in new window or tab >>Feruloylated Arabinoxylans from Wheat Bran: Optimization of Extraction Process and Validation at Pilot Scale
2019 (English)In: ACS Sustainable Chemistry and Engineering, ISSN 2168-0485, Vol. 7, no 15, p. 13167-13177Article in journal (Refereed) Published
Abstract [en]

The extraction of feruloylated arabinoxylan (AX) from wheat bran was optimized in terms of the pretreatments prior to subcritical water extraction and then validated at the pilot scale. Destarching of wheat bran was critical to improve the yields and purity of the extracted AX. Time evolution profiles from sequential extractions revealed differences in the extractability of different polysaccharides, whereby beta-D-glucans were first extracted followed by AX. At longer extraction times, the AX population was more substituted and more uniform in terms of molar mass distribution. Validation of the process at pilot scale (with a scaling factor of 33) resulted in AXs with similar molecular characteristics as in the laboratory scale. Both solid to liquid ratio and extraction time were essential in improving the yields. Our study demonstrated scalability of the process, opening opportunities for the further development of multifunctional food and material products from the extracted AXs.

Place, publisher, year, edition, pages
American Chemical Society (ACS), 2019
Keywords
wheat bran, arabinoxylan (AX), ferulic acid, subcritical water extraction, pilot scale
National Category
Chemical Sciences
Identifiers
urn:nbn:se:kth:diva-257452 (URN)10.1021/acssuschemeng.9b02329 (DOI)000480370500058 ()2-s2.0-85071007087 (Scopus ID)
Note

QC 20190830

Available from: 2019-08-30 Created: 2019-08-30 Last updated: 2019-08-30Bibliographically approved
McKee, L. S., Martinez-Abad, A., Ruthes, A. C., Vilaplana, F. & Brumer, H. (2019). Focused Metabolism of beta-Glucans by the Soil Bacteroidetes Species Chitinophaga pinensis. Applied and Environmental Microbiology, 85(2), Article ID UNSP e02231-18.
Open this publication in new window or tab >>Focused Metabolism of beta-Glucans by the Soil Bacteroidetes Species Chitinophaga pinensis
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2019 (English)In: Applied and Environmental Microbiology, ISSN 0099-2240, E-ISSN 1098-5336, Vol. 85, no 2, article id UNSP e02231-18Article in journal (Refereed) Published
Abstract [en]

The genome and natural habitat of Chitinophaga pinensis suggest it has the ability to degrade a wide variety of carbohydrate-based biomass. Complementing our earlier investigations into the hydrolysis of some plant polysaccharides, we now show that C. pinensis can grow directly on spruce wood and on the fungal fruiting body. Growth was stronger on fungal material, although secreted enzyme activity was high in both cases, and all biomass-induced secretomes showed a predominance of beta-glucanase activities. We therefore conducted a screen for growth on and hydrolysis of beta-glucans isolated from different sources. Most noncrystalline beta-glucans supported good growth, with variable efficiencies of polysaccharide deconstruction and oligosaccharide uptake, depending on the polysaccharide backbone linkage. In all cases, beta-glucan was the only type of polysaccharide that was effectively hydrolyzed by secreted enzymes. This contrasts with the secretion of enzymes with a broad range of activities observed during growth on complex heteroglycans. Our findings imply a role for C. pinensis in the turnover of multiple types of biomass and suggest that the species may have two metabolic modes: a "scavenging mode," where multiple different types of glycan may be degraded, and a more "focused mode" of beta-glucan metabolism. The significant accumulation of some types of beta-gluco-oligosaccharides in growth media may be due to the lack of an appropriate transport mechanism, and we propose that this is due to the specificity of expressed polysaccharide utilization loci. We present a hypothetical model for beta-glucan metabolism by C. pinensis that suggests the potential for nutrient sharing among the microbial litter community. IMPORTANCE It is well known that the forest litter layer is inhabited by a complex microbial community of bacteria and fungi. However, while the importance of fungi in the turnover of natural biomass is well established, the role of their bacterial counterparts is less extensively studied. We show that Chitinophaga pinensis, a prominent member of an important bacterial genus, is capable of using both plant and fungal biomass as a nutrient source but is particularly effective at deconstructing dead fungal material. The turnover of dead fungus is key in natural elemental cycles in the forest. We show that C. pinensis can perform extensive degradation of this material to support its own growth while also releasing sugars that may serve as nutrients for other microbial species. Our work adds detail to an increasingly complex picture of life among the environmental microbiota.

Place, publisher, year, edition, pages
AMER SOC MICROBIOLOGY, 2019
Keywords
beta-glucan polysaccharides, bacteria, Bacteroidetes, biomass recycling, carbohydrate active enzymes, polysaccharide utilization loci
National Category
Botany
Identifiers
urn:nbn:se:kth:diva-242256 (URN)10.1128/AEM.02231-18 (DOI)000455226800019 ()30413479 (PubMedID)2-s2.0-85059797944 (Scopus ID)
Note

QC 20190130

Available from: 2019-01-30 Created: 2019-01-30 Last updated: 2019-01-30Bibliographically approved
Berglund, J., Mikkelsen, D., Flanagan, B., Dhital, S., Henriksson, G., Lindström, M., . . . Vilaplana, F. (2019). Hydrogels of bacterial cellulose and wood hemicelluloses as a model of plant secondary cell walls. Paper presented at National Meeting of the American-Chemical-Society (ACS), MAR 31-APR 04, 2019, Orlando, FL. Abstracts of Papers of the American Chemical Society, 257
Open this publication in new window or tab >>Hydrogels of bacterial cellulose and wood hemicelluloses as a model of plant secondary cell walls
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2019 (English)In: Abstracts of Papers of the American Chemical Society, ISSN 0065-7727, Vol. 257Article in journal, Meeting abstract (Other academic) Published
Place, publisher, year, edition, pages
AMER CHEMICAL SOC, 2019
National Category
Paper, Pulp and Fiber Technology
Identifiers
urn:nbn:se:kth:diva-257620 (URN)000478860502446 ()
Conference
National Meeting of the American-Chemical-Society (ACS), MAR 31-APR 04, 2019, Orlando, FL
Note

QC 20190918

Available from: 2019-09-18 Created: 2019-09-18 Last updated: 2019-10-16Bibliographically approved
Farahani, S. K., Vilaplana, F., Hansson, P. & Wågberg, L. (2019). Influence of solubility on the adsorption of different Xyloglucan fractions to cellulose model surfaces. Paper presented at National Meeting of the American-Chemical-Society (ACS), MAR 31-APR 04, 2019, Orlando, FL. Abstracts of Papers of the American Chemical Society, 257
Open this publication in new window or tab >>Influence of solubility on the adsorption of different Xyloglucan fractions to cellulose model surfaces
2019 (English)In: Abstracts of Papers of the American Chemical Society, ISSN 0065-7727, Vol. 257Article in journal, Meeting abstract (Other academic) Published
Place, publisher, year, edition, pages
AMER CHEMICAL SOC, 2019
National Category
Paper, Pulp and Fiber Technology
Identifiers
urn:nbn:se:kth:diva-257629 (URN)000478860502441 ()
Conference
National Meeting of the American-Chemical-Society (ACS), MAR 31-APR 04, 2019, Orlando, FL
Note

QC 20190902

Available from: 2019-09-02 Created: 2019-09-02 Last updated: 2019-10-15Bibliographically approved
Requena, R., Jimenez-Quero, A., Vargas, M., Moriana Torro, R., Chiralt, A. & Vilaplana, F. (2019). Integral Fractionation of Rice Husks into Bioactive Arabinoxylans, llulose Nanocrystals, and Silica Particles. ACS Sustainable Chemistry and Engineering, 7(6), 6275-6286
Open this publication in new window or tab >>Integral Fractionation of Rice Husks into Bioactive Arabinoxylans, llulose Nanocrystals, and Silica Particles
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2019 (English)In: ACS Sustainable Chemistry and Engineering, ISSN 2168-0485, Vol. 7, no 6, p. 6275-6286Article in journal (Refereed) Published
Abstract [en]

Rice husk is an important agricultural by-product that has not been exploited yet to full capacity for advanced applications. The feasibility of obtaining high-value products such as bioactive hemicelluloses and cellulose nanocrystals (CNCs) from rice husk is here demonstrated in a cascade biorefinery process using subcritical water extraction (SWE) prior to bleaching and acid hydrolysis and compared to traditional alkali pretreatments. The proposed SWE process enables the isolation of bioactive arabinoxylans with phenolic acid moieties, thus preserving their antioxidant and anti- bacterial properties that are lost during alkaline conditions. Bioactive Additionally, SWE can be combined with subsequent arabinoxylan Silica particles bleaching and acid hydrolysis to obtain CNCs with large aspect ratio, high crystallinity, and thermal stability. The hydrothermal process also enables the recovery of silica particles that are lost during the alkali step but can be recovered after the isolation of the CNCs. Our biorefinery strategy results in the integral valorization of rice husk into their molecular components (bioactive arabinoxylans, cellulose nanocrystals, and silica particles), which can be used as additives for food applications and as reinforcing agents in biocomposite materials, respectively.

Place, publisher, year, edition, pages
American Chemical Society (ACS), 2019
Keywords
Rice husk, Subcritical water extraction, Xylans, Cellulose nanocrystals, Biorefinery
National Category
Other Chemistry Topics
Identifiers
urn:nbn:se:kth:diva-248332 (URN)10.1021/acssuschemeng.8b06692 (DOI)000461978200074 ()2-s2.0-85062832429 (Scopus ID)
Note

QC 20190410

Available from: 2019-04-10 Created: 2019-04-10 Last updated: 2019-04-10Bibliographically approved
Sullivan, M. A., Nitschke, S., Skwara, E. P., Wang, P., Zhao, X., Pan, X. S., . . . Nitschke, F. (2019). Skeletal Muscle Glycogen Chain Length Correlates with Insolubility in Mouse Models of Polyglucosan-Associated Neurodegenerative Diseases. Cell reports, 27(5), 1334-1344.e6
Open this publication in new window or tab >>Skeletal Muscle Glycogen Chain Length Correlates with Insolubility in Mouse Models of Polyglucosan-Associated Neurodegenerative Diseases
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2019 (English)In: Cell reports, ISSN 2211-1247, E-ISSN 2211-1247, Vol. 27, no 5, p. 1334-1344.e6Article in journal (Refereed) Published
Abstract [en]

Lafora disease (LD) and adult polyglucosan body disease (APBD) are glycogen storage diseases characterized by a pathogenic buildup of insoluble glycogen. Mechanisms causing glycogen insolubility are poorly understood. Here, in two mouse models of LD (Epm2a(-/-) and Epm2b(-/-)) and one of APBD (Gbe1(ys/ys)), the separation of soluble and insoluble muscle glycogen is described, enabling separate analysis of each fraction. Total glycogen is increased in LD and APBD mice, which, together with abnormal chain length and molecule size distributions, is largely if not fully attributed to insoluble glycogen. Soluble glycogen consists of molecules with distinct chain length distributions and differential corresponding solubility, providing a mechanistic link between soluble and insoluble glycogen in vivo. Phosphorylation states differ across glycogen fractions and mouse models, demonstrating that hyperphosphorylation is not a basic feature of insoluble glycogen. Lastly, model-specific variances in protein and activity levels of key glycogen synthesis enzymes suggest uninvestigated regulatory mechanisms.

Place, publisher, year, edition, pages
cell press, 2019
National Category
Cell Biology
Identifiers
urn:nbn:se:kth:diva-251707 (URN)10.1016/j.celrep.2019.04.017 (DOI)000466484100003 ()31042462 (PubMedID)2-s2.0-85064620718 (Scopus ID)
Note

QC 20190520

Available from: 2019-05-20 Created: 2019-05-20 Last updated: 2019-05-20Bibliographically approved
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ORCID iD: ORCID iD iconorcid.org/0000-0003-3572-7798

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