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Marcos, S., Artal, P., Gatinel, D., Lundström, L., Yoon, G. & Lewis, N. (2025). Introduction to the feature Issue "Improving Vision through Intraocular Lenses": a tribute to Jim Schwiegerling. Biomedical Optics Express, 16(4), 1707-1710
Open this publication in new window or tab >>Introduction to the feature Issue "Improving Vision through Intraocular Lenses": a tribute to Jim Schwiegerling
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2025 (English)In: Biomedical Optics Express, E-ISSN 2156-7085, Vol. 16, no 4, p. 1707-1710Article in journal (Refereed) Published
Abstract [en]

Cataract surgery, a transformative procedure to restore vision, has seen remarkable advancements in intraocular lens (IOL) technologies. This special issue presents a collection of research that explores the performance, design, and evaluation of IOLs. From established designs and the impact of key optical parameters to innovative approaches and preoperative simulations, these contributions offer a comprehensive view of current trends and future directions in IOL development. The special issue also honors the legacy of Prof. Jim Schwiegerling whose contributions to visual optics in general, and IOLs in particular, have had a tremendous impact in the field, both in the academic, clinical and industrial communities.

Place, publisher, year, edition, pages
Optica Publishing Group, 2025
National Category
Ophthalmology
Identifiers
urn:nbn:se:kth:diva-363638 (URN)10.1364/BOE.561537 (DOI)001459715500004 ()40322018 (PubMedID)2-s2.0-105001709615 (Scopus ID)
Note

QC 20250602

Available from: 2025-06-02 Created: 2025-06-02 Last updated: 2025-06-02Bibliographically approved
Marcos, S., Artal, P., Lundström, L. & Yoon, G. (2025). Visual simulation of intraocular lenses: technologies and applications [Invited]. Biomedical Optics Express, 16(3), 1025-1042
Open this publication in new window or tab >>Visual simulation of intraocular lenses: technologies and applications [Invited]
2025 (English)In: Biomedical Optics Express, E-ISSN 2156-7085, Vol. 16, no 3, p. 1025-1042Article in journal (Refereed) Published
Abstract [en]

Cataract surgery requires selecting an intraocular lens (IOL), whose design affects visual outcomes. Traditional IOL evaluation relies on optical models and bench testing, but these methods fall short in simulating perceptual factors crucial to patient experience. Visual simulators, based on different principles including adaptive optics, temporal multiplexing or physical projection of the IOLs, now allow patients and clinicians to preview and compare different IOL designs preoperatively. By simulating real-world interactions of the eye's optics and the visual system with IOLs, these simulators enhance the patient decision-making process, enable personalized cataract surgery, and can aid in regulatory assessments of IOLs by incorporating preoperative patient-reported visual outcomes. Visual simulators incorporate deformable mirrors, spatial light modulators and optotunable lenses as dynamic elements to simulate monofocal, multifocal and extended depth-of-focus IOLs, including newer designs aimed at improving contrast sensitivity, expanding depth of focus, and minimizing visual disturbances. With ongoing advancements, these simulators hold potential for transforming IOL design, regulatory processes, and patient care by providing realistic and patient-centered visual assessments, ultimately leading to more successful, individualized surgical outcomes.

Place, publisher, year, edition, pages
Optica Publishing Group, 2025
National Category
Ophthalmology
Identifiers
urn:nbn:se:kth:diva-361290 (URN)10.1364/BOE.546971 (DOI)001434111600003 ()2-s2.0-86000338370 (Scopus ID)
Note

QC 20250317

Available from: 2025-03-17 Created: 2025-03-17 Last updated: 2025-03-19Bibliographically approved
Christaras, D., Tsoukalas, S., Papadogiannis, P., Börjeson, C., Volny, M., Lundström, L., . . . Ginis, H. (2023). Central and peripheral refraction measured by a novel double-pass instrument. Biomedical Optics Express, 14(6)
Open this publication in new window or tab >>Central and peripheral refraction measured by a novel double-pass instrument
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2023 (English)In: Biomedical Optics Express, ISSN 2156-7085, Vol. 14, no 6Article in journal (Refereed) Published
Abstract [en]

A novel double-pass instrument and its data analysis method for the measurement of central and peripheral refraction is presented and validated in a group of healthy subjects. The instrument acquires in-vivo, non-cycloplegic, double-pass, through-focus images of the eye’s central and peripheral point-spread function (PSF) using an infrared laser source, a tunable lens and a CMOS camera. The through-focus images were analyzed to determine defocus and astigmatism at 0° and 30° visual field. These values were compared to those obtained with a lab-based Hartmann-Shack wavefront sensor. The two instruments provided data showing good correlation at both eccentricities, particularly in the estimation of defocus.

 

Place, publisher, year, edition, pages
Optica Publishing Group, 2023
National Category
Atom and Molecular Physics and Optics
Identifiers
urn:nbn:se:kth:diva-328444 (URN)10.1364/boe.489881 (DOI)001014836500007 ()37342694 (PubMedID)2-s2.0-85162035591 (Scopus ID)
Note

QC 20230612

Available from: 2023-06-09 Created: 2023-06-09 Last updated: 2023-07-14Bibliographically approved
Papadogiannis, P., Börjeson, C. & Lundström, L. (2023). Comparison of optical myopia control interventions: effect on peripheral image quality and vision. Biomedical Optics Express, 14(7), 3125
Open this publication in new window or tab >>Comparison of optical myopia control interventions: effect on peripheral image quality and vision
2023 (English)In: Biomedical Optics Express, ISSN 2156-7085, Vol. 14, no 7, p. 3125-Article in journal (Refereed) Published
Abstract [en]

This study compares the effects on peripheral vision and image quality of four myopia control interventions: a) Perifocal spectacles/ArtOptica, b) Stellest spectacles/Essilor), c) MiyoSmart spectacles/Hoya and d) MiSight contact lenses/CooperVision. Five subjects participated with habitual or no correction as reference. Three techniques were used: 1) Hartmann-Shack sensors for wavefront errors, 2) double-pass imaging system for point-spread-functions (PSF), and 3) peripheral acuity evaluation. The results show that multiple evaluation methods are needed to fully quantify the optical effects of these myopia control interventions. Perifocal was found to make the relative peripheral refraction (RPR) more myopic in all subjects and to interact with the natural optical errors of the eye, hence showing larger variations in the effect on peripheral vision. MiSight had a smaller effect on RPR, but large effect on peripheral vision. Stellest and MiyoSmart also showed small effects on RPR but had broader double-pass PSFs for all participants, indicating reduced retinal contrast. Reduction in peripheral retinal contrast might thereby play a role in slowing myopia progression even when the peripheral refraction does not turn more myopic.

Place, publisher, year, edition, pages
Optica Publishing Group, 2023
National Category
Atom and Molecular Physics and Optics
Identifiers
urn:nbn:se:kth:diva-328443 (URN)10.1364/boe.486555 (DOI)001037192000002 ()37497498 (PubMedID)2-s2.0-85164279648 (Scopus ID)
Note

QC 20230614

Available from: 2023-06-09 Created: 2023-06-09 Last updated: 2023-08-22Bibliographically approved
Lundström, L. (2023). Currently proposed mechanisms and remaining unknowns for optical myopia control treatment: not just peripheral defocus. Investigative Ophthalmology and Visual Science, 64(8), Article ID 17.
Open this publication in new window or tab >>Currently proposed mechanisms and remaining unknowns for optical myopia control treatment: not just peripheral defocus
2023 (English)In: Investigative Ophthalmology and Visual Science, ISSN 0146-0404, E-ISSN 1552-5783, Vol. 64, no 8, article id 17Article in journal, Meeting abstract (Other academic) Published
Place, publisher, year, edition, pages
ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2023
National Category
Biophysics
Identifiers
urn:nbn:se:kth:diva-338227 (URN)001053758300102 ()
Note

QC 20231017

Available from: 2023-10-17 Created: 2023-10-17 Last updated: 2025-02-20Bibliographically approved
Tabernero, J., Lundström, L., Schwarz, C. & Vohnsen, B. (2023). Introduction to Visual and Physiological Optics feature issue of Biomedical Optics Express and JOSA A. Biomedical Optics Express, 14(7), 3853-3855
Open this publication in new window or tab >>Introduction to Visual and Physiological Optics feature issue of Biomedical Optics Express and JOSA A
2023 (English)In: Biomedical Optics Express, E-ISSN 2156-7085, Vol. 14, no 7, p. 3853-3855Article, review/survey (Refereed) Published
Abstract [en]

This feature issue collects articles presented at the tenth Visual and Physiological Optics meeting (VPO2022), held August 29–31, 2022, in Cambridge, UK. This joint feature issue between Biomedical Optics Express and Journal of the Optical Society of America A includes articles that cover the broad range of topics addressed at the meeting and examples of the current state of research in the field.

Place, publisher, year, edition, pages
Optica Publishing Group, 2023
National Category
Atom and Molecular Physics and Optics
Identifiers
urn:nbn:se:kth:diva-333953 (URN)10.1364/BOE.499269 (DOI)001035551200007 ()37497525 (PubMedID)2-s2.0-85165430907 (Scopus ID)
Note

QC 20230818

Available from: 2023-08-18 Created: 2023-08-18 Last updated: 2023-08-24Bibliographically approved
Sharmin, N., Papadogiannis, P., Romashchenko, D., Lundström, L. & Vohnsen, B. (2023). Parafoveal and Perifoveal Accommodation Response to Defocus Changes Induced by a Tunable Lens. Applied Sciences, 13(15), 8645, Article ID 8645.
Open this publication in new window or tab >>Parafoveal and Perifoveal Accommodation Response to Defocus Changes Induced by a Tunable Lens
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2023 (English)In: Applied Sciences, E-ISSN 2076-3417, Vol. 13, no 15, p. 8645-, article id 8645Article in journal (Refereed) Published
Abstract [en]

The accommodative response of the human eye is predominantly driven by foveal vision, but reacts also to off-foveal stimuli. Here, we report on monocular accommodation measurements using parafoveal and perifoveal annular stimuli centered around the fovea and extending up to 8 & DEG; radial eccentricity for young emmetropic and myopic subjects. The stimuli were presented through a sequence of random defocus step changes induced by a pupil-conjugated tunable lens. A Hartmann-Shack wavefront sensor with an infrared beacon was used to measure real-time changes in ocular aberrations up to and including the fourth radial order across a 3 mm pupil at 20 Hz. Our findings show a significant reduction in accommodative response with increased radial eccentricity.

Place, publisher, year, edition, pages
MDPI AG, 2023
Keywords
accommodation, sign of defocus, aberrations, wavefront sensor, tunable lens, parafovea, perifovea, emmetropization, myopia
National Category
Ophthalmology
Identifiers
urn:nbn:se:kth:diva-334747 (URN)10.3390/app13158645 (DOI)001045414600001 ()2-s2.0-85167890802 (Scopus ID)
Note

QC 20230824

Available from: 2023-08-24 Created: 2023-08-24 Last updated: 2023-08-24Bibliographically approved
Romashchenko, D., Papadogiannis, P., Sanchez, M. D., Lundström, L., Van der Mooren, M. & Canovas, C. (2023). Through-focus evaluation of IOL-induced visual symptoms in a see-through system. Investigative Ophthalmology and Visual Science, 64(8), Article ID 2522.
Open this publication in new window or tab >>Through-focus evaluation of IOL-induced visual symptoms in a see-through system
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2023 (English)In: Investigative Ophthalmology and Visual Science, ISSN 0146-0404, E-ISSN 1552-5783, Vol. 64, no 8, article id 2522Article in journal, Meeting abstract (Other academic) Published
Place, publisher, year, edition, pages
ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2023
National Category
Radiology, Nuclear Medicine and Medical Imaging
Identifiers
urn:nbn:se:kth:diva-339622 (URN)001053758307146 ()
Note

QC 20231115

Available from: 2023-11-15 Created: 2023-11-15 Last updated: 2023-11-15Bibliographically approved
Tabernero, J., Lundström, L., Schwarz, C. & Vohnsen, B. (2023). Visual and Physiological Optics: introduction to the joint feature issue in Biomedical Optics Express and Journal of the Optical Society of America A. Optical Society of America. Journal A: Optics, Image Science, and Vision, 40(7), VPO1-VPO2
Open this publication in new window or tab >>Visual and Physiological Optics: introduction to the joint feature issue in Biomedical Optics Express and Journal of the Optical Society of America A
2023 (English)In: Optical Society of America. Journal A: Optics, Image Science, and Vision, ISSN 1084-7529, E-ISSN 1520-8532, Vol. 40, no 7, p. VPO1-VPO2Article in journal, Editorial material (Other academic) Published
Abstract [en]

This feature issue collects articles presented at the tenth Visual and Physiological Optics meeting (VPO2022), held August 29-31, 2022, in Cambridge, UK. This joint feature issue between Biomedical Optics Express and Journal of the Optical Society of America A includes articles that cover the broad range of topics addressed at the meeting and examples of the current state of research in the field.

Place, publisher, year, edition, pages
Optica Publishing Group, 2023
National Category
Atom and Molecular Physics and Optics
Identifiers
urn:nbn:se:kth:diva-333792 (URN)10.1364/JOSAA.499270 (DOI)001033670200001 ()37706749 (PubMedID)2-s2.0-85171235086 (Scopus ID)
Note

QC 20230811

Available from: 2023-08-11 Created: 2023-08-11 Last updated: 2025-05-27Bibliographically approved
Marcos, S., Artal, P., Atchison, D. A., Hampson, K., Legras, R., Lundström, L. & Yoon, G. (2022). Adaptive optics visual simulators: a review of recent optical designs and applications [Invited]. Biomedical Optics Express, 13(12), 6508-6532
Open this publication in new window or tab >>Adaptive optics visual simulators: a review of recent optical designs and applications [Invited]
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2022 (English)In: Biomedical Optics Express, E-ISSN 2156-7085, Vol. 13, no 12, p. 6508-6532Article, review/survey (Refereed) Published
Abstract [en]

In their pioneering work demonstrating measurement and full correction of the eye's optical aberrations, Liang, Williams and Miller, [JOSA A 14, 2884 (1997)] showed improvement in visual performance using adaptive optics (AO). Since then, AO visual simulators have been developed to explore the spatial limits to human vision and as platforms to test non-invasively optical corrections for presbyopia, myopia, or corneal irregularities. These applications have allowed new psychophysics bypassing the optics of the eye, ranging from studying the impact of the interactions of monochromatic and chromatic aberrations on vision to neural adaptation. Other applications address new paradigms of lens designs and corrections of ocular errors. The current paper describes a series of AO visual simulators developed in laboratories around the world, key applications, and current trends and challenges. As the field moves into its second quarter century, new available technologies and a solid reception by the clinical community promise a vigorous and expanding use of AO simulation in years to come.

Place, publisher, year, edition, pages
Optica Publishing Group, 2022
National Category
Ophthalmology
Identifiers
urn:nbn:se:kth:diva-324403 (URN)10.1364/BOE.473458 (DOI)000917262200024 ()36589577 (PubMedID)2-s2.0-85143200378 (Scopus ID)
Note

QC 20230301

Available from: 2023-03-01 Created: 2023-03-01 Last updated: 2023-03-01Bibliographically approved
Organisations
Identifiers
ORCID iD: ORCID iD iconorcid.org/0000-0002-4894-7944

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