Open this publication in new window or tab >>Show others...
2024 (English)In: Soft Matter, ISSN 1744-683X, E-ISSN 1744-6848, Vol. 20, no 38, p. 7573-7577Article in journal (Refereed) Published
Abstract [en]
Heterofunctional polyester dendrimers up to the third generation, containing 21 internally queued bromine atoms, have been successfully synthesized for the first time using a divergent growth approach. Direct azidation reactions enabled the conversion of the bromide groups to clickable azide pendant functionalities. Therapeutic and chemical moeities could then be coupled to the internal azide or bromide functionalities and external hydroxyl groups of the heterofunctional dendrimers through CuAAC, thiol-bromo click and esterification reactions, expanding their potential for biomedical applications.
Place, publisher, year, edition, pages
Royal Society of Chemistry (RSC), 2024
National Category
Polymer Technologies
Identifiers
urn:nbn:se:kth:diva-354899 (URN)10.1039/d4sm00849a (DOI)001315077900001 ()39295579 (PubMedID)2-s2.0-85205604524 (Scopus ID)
Note
QC 20241022
2024-10-162024-10-162024-10-22Bibliographically approved