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Numerical model of the myosin V molecular motor
KTH, School of Industrial Engineering and Management (ITM), Learning.
2018 (English)Independent thesis Advanced level (professional degree), 20 credits / 30 HE creditsStudent thesisAlternative title
Numerisk modell av den molekylära motorn myosin V (Swedish)
Abstract [en]

A variation on a numerical model of the motor protein myosin V presentedin a paper by Craig and Linke (2009) is developed. An alternative potential is proposed. All aspects of the model development arederived in detail and tested. Two model tests are created and used toconfirm the correctness of the developed model. A simulation demonstratesthat the developed model is able to produce a myosin V step. Adidactical transposition is presented in the form of a compendium, in which a numerical model of myosin V by Craig and Linke (2009) isdescribed. The didactical transposition is developed using a methodologyof didactical engineering. The didactical study indicated thatthe content was well recieved by the target group of eight individualsin respect to the scientific complexity and that it evokes motivation forlearning. The study also indicated that unsuccessful areas of the didacticaltransposition existed.

Abstract [sv]

En variation av en numerisk modell av motorproteinet myosin V presenteradav Craig och Linke (2009) utvecklas. En alternativ potential föreslås. Alla aspekter av modellutvecklingen härleds i detalj och testas.Två modelltester skapas och används för att bekräfta riktigheteni den utvecklade modellen. En simulering demonstrerar att myosin Vkan ta ett steg i den utvecklade modellen.En didaktisk transposition presenteras i form av ett kompendium,där en numerisk modell av myosin V av Craig och Linke (2009) beskrivs.Metodologiskt utvecklas den didaktiska transpositionen medhjälp av didaktisk ingenjörskonst. Den didaktiska studien indikeradeatt innehållet togs emot väl av målgruppen bestående av åtta personeri hänseende till vetenskaplig komplexitet och att det väckte motivationför lärande. Studien indikerade även att misslyckade områden av dendidaktiska transpositionen förekom.

Place, publisher, year, edition, pages
2018. , p. 61
Series
TRITA-ITM-EX ; 2018:628
Keywords [en]
Numerical model, myosin V, simulation, biophysics, didactical engineering
Keywords [sv]
Numerisk modell, myosin V, simulering, biofysik, didaktisk ingenjörskonst
National Category
Engineering and Technology Physical Sciences Didactics
Identifiers
URN: urn:nbn:se:kth:diva-233850OAI: oai:DiVA.org:kth-233850DiVA, id: diva2:1243393
External cooperation
Stockholms universitet
Subject / course
Technology and Learning
Educational program
Master of Science in Engineering - Engineering and of Education
Presentation
2018-05-23, 00:00
Supervisors
Examiners
Available from: 2018-09-06 Created: 2018-08-31 Last updated: 2018-09-06Bibliographically approved

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CiteExportLink to record
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Citation style
  • apa
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