Human-robot interaction (HRI) is movingtowards the human-robot synchronization challenge. Inrobots like exoskeletons, this challenge translates to thereliable motion segmentation problem using wearabledevices. Therefore, our paper explores the possibility ofsegmenting the motion reversals of a rigid-IMU clusterusing screw-based invariants. Moreover, we evaluate thereliability of this framework with regard to the sensorplacement, speed and type of motion. Overall, our resultsshow that the screw-based invariants can reliably segmentthe motion reversals of a rigid-IMU cluster.