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A Bioimpedance Spectroscopy Interface for EIM Based on IF-Sampling and Pseudo 2-Path SC Bandpass ΔΣ ADC
KTH, School of Electrical Engineering and Computer Science (EECS), Electrical Engineering, Electronics and Embedded systems. (Mixed-Signals ICs and Systems)ORCID iD: 0000-0001-7549-0858
KTH, School of Electrical Engineering and Computer Science (EECS), Electrical Engineering, Electronics and Embedded systems. (Mixed Signal ICs & Systems)ORCID iD: 0000-0003-1736-8701
KTH, School of Electrical Engineering and Computer Science (EECS), Electrical Engineering, Electronics and Embedded systems. (Mixed Signal ICs & Systems)ORCID iD: 0000-0003-0565-9907
KTH, School of Electrical Engineering and Computer Science (EECS), Electrical Engineering, Electronics and Embedded systems. (Mixed Signal ICs & Systems)ORCID iD: 0000-0003-3802-7834
2024 (English)In: IEEE Transactions on Biomedical Circuits and Systems, ISSN 1932-4545, E-ISSN 1940-9990, p. 1-13Article in journal (Refereed) Epub ahead of print
Abstract [en]

This paper presents a low-noise bioimpedance (bio-Z) spectroscopy interface for electrical impedance myography (EIM) over the 1 kHz to 2 MHz frequency range. The proposed interface employs a sinusoidal signal generator based on direct-digital-synthesis (DDS) to improve the accuracy of the bio-Z reading, and a quadrature low-intermediate frequency (IF) readout to achieve a good noise-to-power efficiency and the required data throughput to detect muscle contractions. The readout is able to measure baseline and time-varying bio-Z by employing robust and power-efficient low-gain IAs and sixth-order single-bit bandpass (BP) ΔΣ ADCs. The proposed bio-Z spectroscopy interface is implemented in a 180 nm CMOS process, consumes 344.3 - 479.3 μ W, and occupies 5.4 mm 2 area. Measurement results show 0.7 mΩ/√Hz sensitivity at 15.625 kHz, 105.8 dB SNR within 4 Hz bandwidth, and a 146.5 dB figure-of-merit. Additionally, recording of EIM in time and frequency domain during contractions of the bicep brachii muscle demonstrates the potential of the proposed bio-Z interface for wearable EIM systems.

Place, publisher, year, edition, pages
Institute of Electrical and Electronics Engineers (IEEE), 2024. p. 1-13
Keywords [en]
Bioimpedance spectroscopy, electrical impedance myography, analog front-end, sinusoidal signal generator, instrumentation amplifier, bandpass sigma-delta modulator, low-noise.
National Category
Electrical Engineering, Electronic Engineering, Information Engineering Medical Engineering
Research subject
Electrical Engineering; Medical Technology
Identifiers
URN: urn:nbn:se:kth:diva-345246DOI: 10.1109/tbcas.2024.3370399Scopus ID: 2-s2.0-85186995458OAI: oai:DiVA.org:kth-345246DiVA, id: diva2:1850586
Funder
Swedish Foundation for Strategic Research, ITM17-0079
Note

QC 20240411

Available from: 2024-04-10 Created: 2024-04-10 Last updated: 2024-04-11Bibliographically approved

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Fernández Schrunder, AlejandroHuang, Yu-KaiRodriguez, SaulRusu, Ana

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IEEE Transactions on Biomedical Circuits and Systems
Electrical Engineering, Electronic Engineering, Information EngineeringMedical Engineering

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