Existing data-driven approaches are not always supported, or only partly implemented, by existing tools, platforms, and services. The study focuses on proposing a novel, theoretical and general model to describe the heating network of buildings. This study will consolidate and abstract access to standardized interfaces, using a transparent interoperability mechanism, the “meta” interface, supporting translation modules to translate from different components or hardware that are commonly used in current heating networks of buildings in Europe. The ICT architecture will be based on state-of-the-art digital twin technologies and methodologies, offering a unified ecosystem for orchestrated deployment of different input/output configurations, and data flow and energy exchanges. This study will further validate the reference ICT architecture using data-driven approaches, applied in a use case that could be considered a typical low-temperature district heating network.