Highly Adhesive Phenolic Compounds as Interfacial Primers for Bone Fracture FixationsShow others and affiliations
2010 (English)In: ACS APPLIED MATERIALS & INTERFACES, ISSN 1944-8244, Vol. 2, no 3, p. 654-657Article in journal (Refereed) Published
Abstract [en]
Bone fractures are today scabilized with screws and metal plates. More complicated Fractures require alternative treatments that exclude harsh surgical conditions. By adapting the benign and UV initiated thiol-ene reaction, we efficiently fabricated triazine-based, fiber-reinforced adhesive patches within 2 s. To enhance their bone adhesion properties, we found that a pre-treatment step of bone surfaces with phenolic dopamine and poly(parahydroxystyrene) compounds was successful. The latter display the greatest E-module of 3.4 MPa in shear strength. All patches exhibited low cytotoxicity and can therefore find potential use in future treatments of bone fractures.
Place, publisher, year, edition, pages
2010. Vol. 2, no 3, p. 654-657
Keywords [en]
bone, fracture, fibre, reinforced, adhesive, FRAP, thiol-ene, primer, DOPA, surface-chemistry, mytilus-edulis, proteins
National Category
Materials Engineering
Identifiers
URN: urn:nbn:se:kth:diva-19328DOI: 10.1021/am100002sISI: 000275825700012PubMedID: 20356264Scopus ID: 2-s2.0-77952295409OAI: oai:DiVA.org:kth-19328DiVA, id: diva2:337375
Funder
Swedish Research Council, 2006-3617
Note
QC 20110114
2010-08-052010-08-052022-06-25Bibliographically approved