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Copper(II) chloride as an efficient reagent for the dehydrogenation of pyridazinone derivatives
Inst. of Pharmaceutical Chemistry, Albert Szent-Gyorgyi Medical Univ., H-6701 Szeged, POB 121, Hungary.ORCID iD: 0000-0002-7552-1076
1995 (English)In: Synthesis (Stuttgart), ISSN 0039-7881, E-ISSN 1437-210X, no 10, p. 1240-1242Article in journal (Refereed) Published
Abstract [en]

A new procedure is described for the preparation of pyridazinones from 4,5-dihydropyridazinones under mild conditions with CuCl2 in MeCN via halogenation and spontaneous HCl elimination. For the trans-hexahydrophthalazin-8(1H)-one 1B*, the HCl elimination is five times faster than for the corresponding cis isomer 1B.
Place, publisher, year, edition, pages
Georg Thieme Verlag KG , 1995. no 10, p. 1240-1242
National Category
Chemical Sciences
Identifiers
URN: urn:nbn:se:kth:diva-317920DOI: 10.1055/s-1995-4079Scopus ID: 2-s2.0-0028856605OAI: oai:DiVA.org:kth-317920DiVA, id: diva2:1695801
Note

QC 20220915

Available from: 2022-09-14 Created: 2022-09-14 Last updated: 2022-09-15Bibliographically approved

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Szabó, Zoltan

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