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A 10-day confinement to normobaric hypoxia impairs toe, but not finger temperature response during local cold stress
KTH, Skolan för teknik och hälsa (STH), Naturvetenskap och biomedicin, Omgivningsfysiologi.ORCID-id: 0000-0002-7440-2171
KTH, Skolan för teknik och hälsa (STH), Naturvetenskap och biomedicin, Omgivningsfysiologi.
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2017 (engelsk)Inngår i: Journal of Thermal Biology, ISSN 0306-4565, E-ISSN 1879-0992Artikkel i tidsskrift (Fagfellevurdert) Published
Abstract [en]

The study examined the effects of a 10-day normobaric hypoxic confinement on the finger and toe temperature responses to local cooling. Eight male lowlanders underwent a normoxic (NC) and, in a separate occasion, a normobaric hypoxic confinement (HC; FO2: 0.154; simulated altitude ~3400 m). Before and after each confinement, subjects immersed for 30 min their right hand and, in a different session, their right foot in 8 °C water, while breathing either room air (AIR) or a hypoxic gas mixture (HYPO). Throughout the cold-water immersion tests, thermal responses were monitored with thermocouples on fingers and toes. Neither confinement influenced thermal responses in the fingers during the AIR or HYPO test. In the foot, by contrast, HC, but not NC, reduced the average toe temperature by ~1.5 °C (p=0.03), both during the AIR and HYPO test. We therefore conclude that a 10-day confinement to normobaric hypoxia per se augments cold-induced vasoconstriction in the toes, but not in the fingers. The mechanism underlying this dissimilarity remains to be established.

sted, utgiver, år, opplag, sider
Elsevier, 2017.
Emneord [en]
CIVD; hand; foot; high altitude
HSV kategori
Identifikatorer
URN: urn:nbn:se:kth:diva-200527DOI: 10.1016/j.jtherbio.2017.01.009Scopus ID: 2-s2.0-85012284252OAI: oai:DiVA.org:kth-200527DiVA, id: diva2:1069506
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QC 20170130

Tilgjengelig fra: 2017-01-29 Laget: 2017-01-29 Sist oppdatert: 2017-11-29bibliografisk kontrollert

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