Endre søk
RefereraExporteraLink to record
Permanent link

Direct link
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Annet format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annet språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf
Arrayed identification of DNA signatures
KTH, Skolan för bioteknologi (BIO), Genteknologi.ORCID-id: 0000-0003-4313-1601
KTH, Skolan för bioteknologi (BIO), Genteknologi.
2007 (engelsk)Inngår i: Expert Review of Molecular Diagnostics, ISSN 1473-7159, Vol. 7, nr 1, s. 65-76Artikkel, forskningsoversikt (Fagfellevurdert) Published
Abstract [en]

Over the last few years, several initiatives have described efforts to combine previously invented techniques in molecular biology with parallel detection principles to sequence or genotype DNA signatures. The Infinium (R) system from Illumina and the Affymetrix GeneChips (R) are two systems suitable for whole-genome scoring of variable positions. However, directed candidate-gene approaches are more cost effective and several academic groups and the private sector provide techniques with moderate typing throughput combined with large sample capacity suiting these needs. Recently, whole-genome sequencing platforms based on the sequencing-by-synthesis principle were presented by 454 Life Sciences and Solexa, showing great potential as alternatives to conventional genotyping approaches. In addition to these sequencing initiatives, many efforts are pursuing novel ideas to facilitate fast and cost-effective whole genome sequencing, such as ligation-based sequencing. Reliable methods for routine resequencing of human genomes as a tool for personalized medicine, however, remain to be developed.

sted, utgiver, år, opplag, sider
2007. Vol. 7, nr 1, s. 65-76
Emneord [en]
array, genome-wide, genotyping, sequencing, SNP, whole genome, single nucleotide polymorphisms, allele-specific hybridization, rolling-circle amplification, refractory mutation system, polymerase chain-reaction, human-genome, padlock probes, oligonucleotide arrays, molecular beacons, mass-spectrometry
HSV kategori
Identifikatorer
URN: urn:nbn:se:kth:diva-16352DOI: 10.1586/14737159.7.1.65ISI: 000243847500008Scopus ID: 2-s2.0-33846305784OAI: oai:DiVA.org:kth-16352DiVA, id: diva2:334394
Merknad
QC 20100525Tilgjengelig fra: 2010-08-05 Laget: 2010-08-05 Sist oppdatert: 2010-08-31bibliografisk kontrollert

Open Access i DiVA

Fulltekst mangler i DiVA

Andre lenker

Forlagets fulltekstScopus

Søk i DiVA

Av forfatter/redaktør
Lundeberg, JoakimAhmadian, Afshin
Av organisasjonen

Søk utenfor DiVA

GoogleGoogle Scholar

doi
urn-nbn

Altmetric

doi
urn-nbn
Totalt: 49 treff
RefereraExporteraLink to record
Permanent link

Direct link
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Annet format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annet språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf