Particle laden flows with reactive particles are common in industrial applications. Chemical reactions inside the particle or deposition at the surface can generate additional flow phenomena that affect the heat, mass and momentum transfer between the particle and bulk flow. This work aims at investigating the effect of Stefan flow on the drag coefficient of a spherical particle immersed in a uniform flow. Fully resolved 3D simulations were carried out for particle Reynolds numbers based on the free stream velocity ranging from 0.5 to 3. Simulations are carried out in foam-extend CFD software, using the Immersed Boundary(IB) method for treating fluid-solid interactions. The simulations were validated against data for particles without reactive flow, and against the analytical solution for Stefan flow around a particle in a quiescent fluid. We found that in the considered range of Reynolds number the drag coefficient decreases linearly with in increase in Stefan flow velocity.