Ändra sökning
RefereraExporteraLänk till posten
Permanent länk

Direktlänk
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Annat format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annat språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf
Arrayed identification of DNA signatures
KTH, Skolan för bioteknologi (BIO), Genteknologi.ORCID-id: 0000-0003-4313-1601
KTH, Skolan för bioteknologi (BIO), Genteknologi.
2007 (Engelska)Ingår i: Expert Review of Molecular Diagnostics, ISSN 1473-7159, Vol. 7, nr 1, s. 65-76Artikel, forskningsöversikt (Refereegranskat) Published
Abstract [en]

Over the last few years, several initiatives have described efforts to combine previously invented techniques in molecular biology with parallel detection principles to sequence or genotype DNA signatures. The Infinium (R) system from Illumina and the Affymetrix GeneChips (R) are two systems suitable for whole-genome scoring of variable positions. However, directed candidate-gene approaches are more cost effective and several academic groups and the private sector provide techniques with moderate typing throughput combined with large sample capacity suiting these needs. Recently, whole-genome sequencing platforms based on the sequencing-by-synthesis principle were presented by 454 Life Sciences and Solexa, showing great potential as alternatives to conventional genotyping approaches. In addition to these sequencing initiatives, many efforts are pursuing novel ideas to facilitate fast and cost-effective whole genome sequencing, such as ligation-based sequencing. Reliable methods for routine resequencing of human genomes as a tool for personalized medicine, however, remain to be developed.

Ort, förlag, år, upplaga, sidor
2007. Vol. 7, nr 1, s. 65-76
Nyckelord [en]
array, genome-wide, genotyping, sequencing, SNP, whole genome, single nucleotide polymorphisms, allele-specific hybridization, rolling-circle amplification, refractory mutation system, polymerase chain-reaction, human-genome, padlock probes, oligonucleotide arrays, molecular beacons, mass-spectrometry
Nationell ämneskategori
Biologiska vetenskaper
Identifikatorer
URN: urn:nbn:se:kth:diva-16352DOI: 10.1586/14737159.7.1.65ISI: 000243847500008Scopus ID: 2-s2.0-33846305784OAI: oai:DiVA.org:kth-16352DiVA, id: diva2:334394
Anmärkning
QC 20100525Tillgänglig från: 2010-08-05 Skapad: 2010-08-05 Senast uppdaterad: 2010-08-31Bibliografiskt granskad

Open Access i DiVA

Fulltext saknas i DiVA

Övriga länkar

Förlagets fulltextScopus

Sök vidare i DiVA

Av författaren/redaktören
Lundeberg, JoakimAhmadian, Afshin
Av organisationen
Genteknologi
Biologiska vetenskaper

Sök vidare utanför DiVA

GoogleGoogle Scholar

doi
urn-nbn

Altmetricpoäng

doi
urn-nbn
Totalt: 49 träffar
RefereraExporteraLänk till posten
Permanent länk

Direktlänk
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Annat format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annat språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf