Ändra sökning
RefereraExporteraLänk till posten
Permanent länk

Direktlänk
Referera
Referensformat
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Annat format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annat språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf
Positive "framing" as a powerful medication for pain: A meta-analysis of randomized trials
University of Oxford.ORCID-id: 0000-0003-0280-7206
University of Oxford.
University of Oxford, United Kingdom.ORCID-id: 0000-0001-9730-2133
University of Southampton.
Visa övriga samt affilieringar
2016 (Engelska)Ingår i: European Journal of Integrative Medicine, ISSN 1876-3820, E-ISSN 1876-3839, Vol. 8, s. 57-59Artikel i tidskrift (Refereegranskat) Published
Abstract [en]

Introduction: A growing body of evidence suggests that positive framing–inducing positive expectations about the outcome of treatments can reduce pain symptoms. However there is no pooled estimate of the effect size of positive framing for treating pain. Such an estimate is useful to understand the extent to which positive expectations can enhance usual care.

Methods: We extracted data from a recent systematic review of interventions that modified all "context factors" (including but not limited to) inducing positive expectations) in adults suffering from pain. The systematic review concluded that positive expectations were effective, but did not pool the results so no effect size was provided. Two authors independently extracted data from the studies and conducted the analysis. Our primary outcome was patient self-reported pain.

Results: 10 randomized trials were eligible for meta-analysis. In the trials with continuous outcomes the standardized effect size was −0.39 (95% confidence interval −0.68 to −0.10, p = 0.009, I2 = 79%), suggesting reduced pain on average in groups in which positive expectations were induced. The effect size was similar in magnitude but was not statistically significant when we excluded studies deemed to have a high risk of bias (standard effect size −0.31, 95% CI −0.65 to 0.02, p = 0.07, I2 = 77%).

Conclusion: The effect of inducing positive expectations is comparable to the effects of some pharmacological drugs. However many of the studies had a high risk of bias, and heterogeneity was significant. Future research is warranted including investigating ways to implement this evidence into patient care in an ethical way.

Ort, förlag, år, upplaga, sidor
Elsevier, 2016. Vol. 8, s. 57-59
Nationell ämneskategori
Klinisk medicin
Forskningsämne
Filosofi; Medicinsk teknologi
Identifikatorer
URN: urn:nbn:se:kth:diva-192638DOI: 10.1016/j.eujim.2016.08.136OAI: oai:DiVA.org:kth-192638DiVA, id: diva2:971550
Forskningsfinansiär
EU, Europeiska forskningsrådet, 639276
Anmärkning

QC 20160930

Tillgänglig från: 2016-09-16 Skapad: 2016-09-16 Senast uppdaterad: 2017-11-21Bibliografiskt granskad

Open Access i DiVA

Fulltext saknas i DiVA

Övriga länkar

Förlagets fulltexthttp://dx.doi.org/10.1016/j.eujim.2016.08.136

Personposter BETA

Howick, JeremyMebius, Alexander

Sök vidare i DiVA

Av författaren/redaktören
Howick, JeremyMebius, Alexander
I samma tidskrift
European Journal of Integrative Medicine
Klinisk medicin

Sök vidare utanför DiVA

GoogleGoogle Scholar

doi
urn-nbn

Altmetricpoäng

doi
urn-nbn
Totalt: 158 träffar
RefereraExporteraLänk till posten
Permanent länk

Direktlänk
Referera
Referensformat
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Annat format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annat språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf