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Spectral shaping for photon counting digital mammography
KTH, Skolan för teknikvetenskap (SCI), Fysik.
KTH, Skolan för teknikvetenskap (SCI), Fysik.
KTH, Skolan för teknikvetenskap (SCI), Fysik.
KTH, Skolan för teknikvetenskap (SCI), Fysik.ORCID-id: 0000-0002-3039-9791
2007 (Engelska)Ingår i: Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, ISSN 0168-9002, E-ISSN 1872-9576, Vol. 580, nr 2, s. 1046-1049Artikel i tidskrift (Refereegranskat) Published
Abstract [en]

The spectral shaping properties of conventional filters have been evaluated for a photon counting digital mammography system, and the result has been compared with the theoretical spectrum from a multi-prism X-ray lens (MPL). The absorption filters and the MPL were evaluated using a theoretical model of the system which has been verified experimentally. The spectral shaping performance is quantified with the spectral quantum efficiency (SQE), calculated as the polychromatic signal-difference-to-noise ratio (SDNR) squared over the optimal monochromatic SDNR squared at the same average glandular dose. The MPL increases the SQE by 25% compared to the investigated absorption filter when compared with a Tungsten anode. This translates into a potential dose reduction of 20% at maintained SDNR.

Ort, förlag, år, upplaga, sidor
2007. Vol. 580, nr 2, s. 1046-1049
Nyckelord [en]
mammography; photon counting; spectrum; filter; X-ray optics; multi-prism lens
Nationell ämneskategori
Medicinsk laboratorie- och mätteknik
Identifikatorer
URN: urn:nbn:se:kth:diva-6940DOI: 10.1016/j.nima.2007.06.087ISI: 000250128000046Scopus ID: 2-s2.0-34548514027OAI: oai:DiVA.org:kth-6940DiVA, id: diva2:11795
Anmärkning
QC 20100825. Uppdaterad från Accepted till Published 20100825. Konferens: 3rd International Conference on Imaging Techniques in Subatomic Physics, Astrophysics, Medicine, Biology and Industry, Stockholm, SWEDEN, JUN 27-30, 2006.Tillgänglig från: 2007-03-30 Skapad: 2007-03-30 Senast uppdaterad: 2017-12-14Bibliografiskt granskad
Ingår i avhandling
1. Digital Mammography with a Photon Counting Detector in a Scanned Multislit Geometry
Öppna denna publikation i ny flik eller fönster >>Digital Mammography with a Photon Counting Detector in a Scanned Multislit Geometry
2007 (Engelska)Doktorsavhandling, sammanläggning (Övrigt vetenskapligt)
Abstract [en]

Mammography screening aims to reduce the number of breast cancer deaths by early detection of the disease, which is one of the leading causes of deaths for middle aged women in the western world. The risk from the x-ray radiation in mammography is relatively low but still a factor in the benefit-risk ratio of screening. The characterization and optimization of a digital mammography system is presented in this thesis. The investigated system is shown to be highly dose efficient by employing a photon counting detector in a scanning multislit geometry.

A novel automatic exposure control (AEC) is proposed and validated in clinical practise. The AEC uses the leading detector edge to measure the transmission of the breast. The exposure is modulated by altering the scan velocity during the scan. A W-Al anode-filter combination is proposed.

The characterization of the photon counting detector is performed using the detective quantum efficiency. The effect of the photon counting detector and the multislit geometry on the measurement method is studied in detail. It is shown that the detector has a zero-frequency DQE of over 70\% and that it is quantum limited even at very low exposures.

Efficient rejection of image-degrading secondary radiation is fundamental for a dose efficient system. The efficiency of the scatter rejection techniques currently used are quantified and compared to the multislit geometry.

A system performance metric with its foundation in statistical decision theory is discussed. It is argued that a photon counting multislit system can operate at approximately half the dose compared to several other digital mammography techniques.

Ort, förlag, år, upplaga, sidor
Stockholm: KTH, 2007. s. viii, 41
Serie
Trita-FYS, ISSN 0280-316X ; 2007:28
Nyckelord
mammography, digital, photon counting, scanning, detective quantum effciency, scattered radiation, automatic exposure control
Nationell ämneskategori
Fysik
Identifikatorer
urn:nbn:se:kth:diva-4322 (URN)978-91-7178-622-7 (ISBN)
Disputation
2007-04-20, Sal F3, KTH, Lindstedtsvägen 26, Stockholm, 14:00
Opponent
Handledare
Anmärkning
QC 20100825Tillgänglig från: 2007-03-30 Skapad: 2007-03-30 Senast uppdaterad: 2010-08-25Bibliografiskt granskad

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Åslund, MagnusFredenberg, ErikCederström, BjörnDanielsson, Mats
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Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment
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