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An eco-compatible access to diversified bisoxazolone and bisimidazole derivatives
Jouf Univ, Coll Sci, Chem Dept, POB 72341, Sakaka, Aljouf, Saudi Arabia.;Fayoum Univ, Fac Sci, Chem Dept, POB 63514, Fayoum City, Egypt..
KTH, School of Engineering Sciences in Chemistry, Biotechnology and Health (CBH), Chemistry. Nucl Mat Author, POB 530, Cairo, Egypt..
2018 (English)In: ARKIVOC, ISSN 1551-7004, E-ISSN 1551-7012, p. 338-353Article in journal (Refereed) Published
Abstract [en]

An efficient, straight-forward and eco-friendly synthetic strategy for the assembly of novel bisoxazolones via a four-component, sequential reaction of dialdehydes, glycine, benzoyl chloride and acetic anhydride, using ultrasound radiation, is described. Additionally, a diverse group of new bisimidazoles has been synthesized in good yields by the sonication of diamines and (Z)-4-arylidene-2-phenyloxazol-5(4H)-ones. These approaches have resulted in a number of successful routes for the facile synthesis of bis-oxazolone and bis-imidazole frameworks within minutes of irradiation. Excellent outcomes using these environmentally-friendly parameters make these synthetic schemes ideal, sustainable, green-chemistry procedures and provide simple access towards the preparation of bisheterocycles. [GRAPHICS] .

Place, publisher, year, edition, pages
Arkat , 2018. p. 338-353
Keywords [en]
Bisoxazolones, bis-imidazoles, solvent-free, ultrasound-assisted, multi-component synthesis
National Category
Chemical Sciences
Identifiers
URN: urn:nbn:se:kth:diva-232806DOI: 10.24820/ark.5550190.p010.544ISI: 000438799100028Scopus ID: 2-s2.0-85049185514OAI: oai:DiVA.org:kth-232806DiVA, id: diva2:1236480
Note

QC 20180802

Available from: 2018-08-02 Created: 2018-08-02 Last updated: 2019-10-08Bibliographically approved

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