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Demonstration of the first self-sealing aerosol spray nozzle for medical drug delivery
KTH, School of Electrical Engineering and Computer Science (EECS), Micro and Nanosystems.ORCID iD: 0000-0001-9947-5011
KTH, School of Electrical Engineering and Computer Science (EECS), Micro and Nanosystems.ORCID iD: 0000-0001-9552-4234
KTH, School of Electrical Engineering and Computer Science (EECS), Micro and Nanosystems.ORCID iD: 0000-0001-9552-4234
2019 (English)In: Demonstration of first self-sealing aerosol spray nozzle for medical drug delivery, 2019, Vol. 32, p. 1-4Conference paper, Oral presentation with published abstract (Refereed)
Abstract [en]

Portable medical inhaler systems are prone to bacterial contamination and ingrowth. Here we demonstrate thefirst valved aerosol spray chip, a system that sprays a microjet when actuated and seals against bacterial ingrowth into the spray nozzle in the closed state by a sufficiently small gap. The sealing mechanism is realized by placing a valve seat directly underneath the spray orifices. We fabricated and characterized spray chips with and without valve mechanism and show that they haveindistinguishable spray performance. Our system aims to enable the safe reuse of spray chips for multiple spray operations over an extended period, lowering the cost of treatment while increasing patient compliance.

Place, publisher, year, edition, pages
2019. Vol. 32, p. 1-4
Keywords [en]
BioMEMS, drug delivery, fluidic microjet, inertial microfluidics, respiratory tract disease treatment
National Category
Medical and Health Sciences Medical Engineering
Research subject
Medical Technology
Identifiers
URN: urn:nbn:se:kth:diva-251748OAI: oai:DiVA.org:kth-251748DiVA, id: diva2:1316855
Conference
IEEE 32nd International Conference on Micro Electro Mechanical Systems (MEMS)
Note

QC 20190819

Available from: 2019-05-21 Created: 2019-05-21 Last updated: 2019-08-19Bibliographically approved

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Roxhed, NiclasStemme, Göran

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Output format
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