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Structural analysis and biological activity of cell wall polysaccharides extracted from Panax ginseng marc
KTH, Skolan för kemi, bioteknologi och hälsa (CBH), Kemi, Glykovetenskap.ORCID-id: 0000-0001-5007-2705
KTH, Skolan för kemi, bioteknologi och hälsa (CBH), Kemi, Glykovetenskap.ORCID-id: 0000-0002-6965-1931
Adelaide Glycomics, School of Agriculture, Food and Wine, University of Adelaide, Waite Campus, Urrbrae, SA 5064, Australia.
Genomics Research Centre, Academia Sinica, Sec. 2, 128 Academia Road, Nankang, Taipei 115, Taiwan.
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2019 (Engelska)Ingår i: International Journal of Biological Macromolecules, ISSN 0141-8130, E-ISSN 1879-0003, Vol. 135, s. 29-37Artikel i tidskrift (Refereegranskat) Published
Abstract [en]

Ginseng marc is a major by-product of the ginseng industry currently used as animal feed or fertilizer. This fibrous, insoluble waste stream is rich in cell wall polysaccharides and therefore a potential source of ingredients for functional food with health-promoting properties. However, the extraction of these polysaccharides has proved problematic and their exact composition remains unknown. Here we have analysed the composition, structure and biological activity of polysaccharides from ginseng root, stem and leaf marc fractionated using a chelator and alkali solutions. The pectic fraction has been extracted from root marc in high abundance and can activate the production of interleukine-1α and the hematopoietic growth factor by RAW 264.7 murine macrophage cells, which are important immune regulators of T-cells during inflammatory responses and infection processes. Our study reveals the potential to increase the value of ginseng marc by generating carbohydrate-based products with a higher value than animal feed.

Ort, förlag, år, upplaga, sidor
Elsevier, 2019. Vol. 135, s. 29-37
Nyckelord [en]
Ginseng marc, Cell wall polysaccharides, Structure, Murine macrophage cells
Nationell ämneskategori
Polymerkemi Livsmedelsvetenskap Läkemedelsbioteknik
Forskningsämne
Fiber- och polymervetenskap
Identifikatorer
URN: urn:nbn:se:kth:diva-252310DOI: 10.1016/j.ijbiomac.2019.05.077ISI: 000477691600004Scopus ID: 2-s2.0-85066087024OAI: oai:DiVA.org:kth-252310DiVA, id: diva2:1318100
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QC 20190527

Tillgänglig från: 2019-05-26 Skapad: 2019-05-26 Senast uppdaterad: 2019-09-25Bibliografiskt granskad

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Li, JingWang, DamaoBulone, VincentHsieh, Yves S. Y.

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Li, JingWang, DamaoBulone, VincentHsieh, Yves S. Y.
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GlykovetenskapWallenberg Wood Science Center
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International Journal of Biological Macromolecules
PolymerkemiLivsmedelsvetenskapLäkemedelsbioteknik

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