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Review on Acoustic Droplet Vaporization in Ultrasound Diagnostics and Therapeutics
KTH, School of Engineering Sciences in Chemistry, Biotechnology and Health (CBH), Biomedical Engineering and Health Systems, Medical Imaging. (Contrast Enhanced Medical Imaging)ORCID iD: 0000-0003-2589-9780
KTH, School of Engineering Sciences in Chemistry, Biotechnology and Health (CBH), Biomedical Engineering and Health Systems, Medical Imaging. (Contrast Enhanced Medical Imaging)ORCID iD: 0000-0002-3699-396X
KTH, School of Engineering Sciences in Chemistry, Biotechnology and Health (CBH), Biomedical Engineering and Health Systems, Medical Imaging. Mechatronics Engineering Program, Faculty of Engineering and Natural Science, Sabanci University, Istanbul 34956, Turkey. (Contrast Enhanced Medical Imaging)ORCID iD: 0000-0003-4883-7347
2019 (English)In: BioMed Research International, ISSN 2314-6133, E-ISSN 2314-6141, article id 9480193Article, review/survey (Refereed) Published
Abstract [en]

Acoustic droplet vaporization (ADV) is the physical process in which liquid undergoes phase transition to gas after exposure to a pressure amplitude above a certain threshold. In recent years, new techniques in ultrasound diagnostics and therapeutics have been developed which utilize microformulations with various physical and chemical properties. The purpose of this review is to give the reader a general idea on how ADV can be implemented for the existing biomedical applications of droplet vaporization. In this regard, the recent developments in ultrasound therapy which shed light on the ADV are considered. Modern designs of capsules and nanodroplets (NDs) are shown, and the material choices and their implications for function are discussed. The influence of the physical properties of the induced acoustic field, the surrounding medium, and thermophysical effects on the vaporization are presented. Lastly, current challenges and potential future applications towards the implementation of the therapeutic droplets are discussed.

Place, publisher, year, edition, pages
2019. article id 9480193
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Other Medical Engineering
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URN: urn:nbn:se:kth:diva-255030DOI: 10.1155/2019/9480193ISI: 000477811000001Scopus ID: 2-s2.0-85070102699OAI: oai:DiVA.org:kth-255030DiVA, id: diva2:1337481
Note

QC 20190716

Available from: 2019-07-15 Created: 2019-07-15 Last updated: 2019-08-20Bibliographically approved

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Loskutova, KseniaGrishenkov, DmitryGhorbani, Morteza

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