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Biolubrication synergy: Hyaluronan - Phospholipid interactions at interfaces
KTH, Skolan för kemi, bioteknologi och hälsa (CBH), Kemi, Yt- och korrosionsvetenskap. KTH Royal Inst Technol, Sch Engn Sci Chem Biotechnol & Hlth, Dept Chem Surface & Corros Sci, Drottning Kristinas Vag 51, SE-10044 Stockholm, Sweden..ORCID-id: 0000-0002-2288-819X
Helmholtz Zentrum Geesthacht, Ctr Mat & Costal Res, Inst Mat Res, Max Planck Str 1, D-21502 Geesthacht, Germany..
UTP Univ Sci & Technol, Inst Math & Phys, Al Kaliskiego 7, PL-85796 Bydgoszcz, Poland.;Friedrich Alexander Univ Erlangen Nurnberg, Cluster Excellence Engn Adv Mat, Inst Multiscale Simulat, Cauerstr 3, D-91058 Erlangen, Germany..
KTH, Skolan för kemi, bioteknologi och hälsa (CBH), Kemi, Yt- och korrosionsvetenskap.
2019 (engelsk)Inngår i: Advances in Colloid and Interface Science, ISSN 0001-8686, E-ISSN 1873-3727, Vol. 274, artikkel-id UNSP 102050Artikkel i tidsskrift (Fagfellevurdert) Published
Abstract [en]

The manner in which nature has solved lubrication issues has fascinated scientists for centuries, in particular when considering that lubrication is achieved in aqueous media. The most outstanding system in this respect is likely the synovial joint, where close to frictionless motion is realized under different loads and shear rates. This review article focuses on two components present in the synovial area, hyaluronan and phospholipids. We recapitulate what has been learned about their interactions at interfaces from recent experiments, with focus on results obtained using reflectivity techniques at large scale facilities. In parallel, modelling experiments have been carried out and from these efforts new detailed knowledge about how hyaluronan and phospholipids interact has been gained. In this review we combine findings from modelling and experiments to gain deeper insight. Finally, we summarize what has been learned of the lubrication performance of mixtures of phospholipids and hyaluronan.

sted, utgiver, år, opplag, sider
ELSEVIER , 2019. Vol. 274, artikkel-id UNSP 102050
Emneord [en]
Lubrication synergy, Hyaluronan, Phospholipid, Association, Interface structure
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Identifikatorer
URN: urn:nbn:se:kth:diva-266021DOI: 10.1016/j.cis.2019.102050ISI: 000500385100004PubMedID: 31669714Scopus ID: 2-s2.0-85073965935OAI: oai:DiVA.org:kth-266021DiVA, id: diva2:1380869
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QC 20191219

Tilgjengelig fra: 2019-12-19 Laget: 2019-12-19 Sist oppdatert: 2020-01-13bibliografisk kontrollert

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