kth.sePublications
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Long-term prognosis after a first myocardial infarction: eight years follow up of the case-control study PAROKRANK
Karolinska Inst, Dept Med Solna, Cardiol Unit, Stockholm, Sweden..
Karolinska Inst, Dept Med Solna, Cardiol Unit, Stockholm, Sweden..
Karolinska Inst, Dept Dent Med, Div Periodontol, Stockholm, Sweden..
Karolinska Inst, Dept Med Solna, Cardiol Unit, Stockholm, Sweden.;Karolinska Inst, Inst Environm Med, Sect Cardiovasc Epidemiol, Stockholm, Sweden..
Show others and affiliations
2022 (English)In: Scandinavian Cardiovascular Journal, ISSN 1401-7431, E-ISSN 1651-2006, Vol. 56, no 1, p. 337-342Article in journal (Refereed) Published
Abstract [en]

Objective. To explore long-term cardiovascular outcomes and mortality in patients after a first myocardial infarction (MI) compared with matched controls in a contemporary setting. Methods. During 2010-2014 the Swedish study PAROKRANK recruited 805 patients <75 years with a first MI and 805 age-, gender-, and area-matched controls. All study participants were followed until 31 December 2018, through linkage with the National Patient Registry and the Cause of Death Registry. The primary endpoint was the first of a composite of all-cause death, non-fatal MI, non-fatal stroke, and heart failure hospitalization. Event rates in cases and controls were calculated using a Cox regression model, subsequently adjusted for baseline smoking, education level, and marital status. Kaplan-Meier curves were computed and compared by log-rank test. Results. A total of 804 patients and 800 controls (mean age 62 years; women 19%) were followed for a mean of 6.2 (0.2-8.5) years. The total number of primary events was 211. Patients had a higher event rate than controls (log-rank test p < .0001). Adjusted hazard ratio (HR) for the primary outcome was 2.04 (95% CI 1.52-2.73). Mortality did not differ between patients (n = 38; 4.7%) and controls (n = 35; 4.4%). A total of 82.5% patients and 91.3% controls were event-free during the follow up. Conclusions. In this long-term follow up of a contemporary, case-control study, the risk for cardiovascular events was higher in patients with a previous first MI compared with their matched controls, while mortality did not differ. The access to high quality of care and cardiac rehabilitation might partly explain the low rates of adverse outcomes.

Place, publisher, year, edition, pages
Informa UK Limited , 2022. Vol. 56, no 1, p. 337-342
Keywords [en]
Cardiovascular prevention, case-control study, long-term outcome, myocardial infarction, PAROKRANK
National Category
Cardiac and Cardiovascular Systems
Identifiers
URN: urn:nbn:se:kth:diva-316946DOI: 10.1080/14017431.2022.2112072ISI: 000841682000001PubMedID: 35974709Scopus ID: 2-s2.0-85136039545OAI: oai:DiVA.org:kth-316946DiVA, id: diva2:1692248
Note

QC 20220912

Available from: 2022-09-01 Created: 2022-09-01 Last updated: 2022-09-12Bibliographically approved

Open Access in DiVA

No full text in DiVA

Other links

Publisher's full textPubMedScopus

Authority records

Näsman, Per

Search in DiVA

By author/editor
Näsman, Per
By organisation
Centre for Traffic Research, CTR
In the same journal
Scandinavian Cardiovascular Journal
Cardiac and Cardiovascular Systems

Search outside of DiVA

GoogleGoogle Scholar

doi
pubmed
urn-nbn

Altmetric score

doi
pubmed
urn-nbn
Total: 24 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf