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The genome sequence of Mycoplasma mycoides subsp mycoides SC type strain PG1(T), the causative agent of contagious bovine pleuropneumonia (CBPP)
KTH, Tidigare Institutioner, Bioteknologi.
KTH, Tidigare Institutioner, Bioteknologi.
KTH, Tidigare Institutioner, Bioteknologi.
Vise andre og tillknytning
2004 (engelsk)Inngår i: Genome Research, ISSN 1088-9051, E-ISSN 1549-5469, Vol. 14, nr 2, s. 221-227Artikkel i tidsskrift (Fagfellevurdert) Published
Abstract [en]

Mycoplasma mycoides subsp. mycoidesSC (MmymySC) is the etiological agent of contagious bovine pleuropneumonia (CBPP), a highly contagious respiratory disease in cattle. The genome of Mmymy SC type strain PUT has been sequenced to map all the genes and to facilitate further studies regarding the cell function of the organism and CBPP. The genome is characterized by a single circular chromosome of 1,211,703 bp with the lowest G+C content (24 mole%) and the highest density of insertion sequences (13% of the genome size) of all sequenced bacterial genomes. The genome contains 985 putative genes, of which 72 are part of insertion sequences and encode transposases. Anomalies in the GC-skew pattern and the presence of large repetitive sequences indicate a high genomic plasticity. A variety of potential virulence factors was identified, including genes encoding putative variable surface proteins and enzymes and transport proteins responsible for the production of hydrogen peroxide and the capsule, which is believed to have toxic effects on the animal.

sted, utgiver, år, opplag, sider
2004. Vol. 14, nr 2, s. 221-227
Emneord [en]
small-colony type, ureaplasma-urealyticum, rna genes, identification, cluster, cattle, classification, annotation, phylogeny, program
HSV kategori
Identifikatorer
URN: urn:nbn:se:kth:diva-23151DOI: 10.1101/gr.1673304ISI: 000188811800003PubMedID: 14762060Scopus ID: 2-s2.0-1242296870OAI: oai:DiVA.org:kth-23151DiVA, id: diva2:341849
Merknad
QC 20100525 QC 20111031Tilgjengelig fra: 2010-08-10 Laget: 2010-08-10 Sist oppdatert: 2020-03-09bibliografisk kontrollert

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Uhlén, Mathias

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Westberg, JoakimPersson, AnjaHolmberg, Anders H.Lundeberg, JoakimPettersson, BertilUhlén, Mathias
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