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A photon-counting silicon-strip detector for digital mammography with an ultrafast 0.18-mu m CMOS ASIC
KTH, Skolan för teknikvetenskap (SCI), Fysik, Medicinsk bildfysik.ORCID-id: 0000-0001-8560-3262
KTH, Skolan för teknikvetenskap (SCI), Fysik, Medicinsk bildfysik.
KTH, Skolan för teknikvetenskap (SCI), Fysik, Medicinsk bildfysik.
KTH, Skolan för teknikvetenskap (SCI), Fysik, Medicinsk bildfysik.ORCID-id: 0000-0002-5092-8822
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2014 (Engelska)Ingår i: Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, ISSN 0168-9002, E-ISSN 1872-9576, Vol. 749, s. 1-6Artikel i tidskrift (Refereegranskat) Published
Abstract [en]

We have evaluated a silicon-strip detector with a 0.18-mu m CMOS application specific integrated circuits (ASIC) containing 160 channels for use in photon-counting digital mammography. Measurements were performed at the Elettra light source using monochromatic X-ray beams with different energies and intensities. Energy resolution, Delta E/E-in, was measured to vary between 0.10 and 0.23 in the energy range of 15-40 keV. Pulse pileup has shown little effect on energy resolution.

Ort, förlag, år, upplaga, sidor
Elsevier, 2014. Vol. 749, s. 1-6
Nyckelord [en]
Mammography, Charge sharing, ASIC, Energy resolution
Nationell ämneskategori
Radiologi och bildbehandling
Identifikatorer
URN: urn:nbn:se:kth:diva-145253DOI: 10.1016/j.nima.2014.02.033ISI: 000334075000001Scopus ID: 2-s2.0-84896521372OAI: oai:DiVA.org:kth-145253DiVA, id: diva2:717612
Anmärkning

QC 20140516

Tillgänglig från: 2014-05-16 Skapad: 2014-05-15 Senast uppdaterad: 2024-03-15Bibliografiskt granskad
Ingår i avhandling
1. Characterization and Optimization of Silicon-strip Detectors for Mammography and Computed Tomography
Öppna denna publikation i ny flik eller fönster >>Characterization and Optimization of Silicon-strip Detectors for Mammography and Computed Tomography
2016 (Engelska)Doktorsavhandling, sammanläggning (Övrigt vetenskapligt)
Abstract [en]

The goal in medical x-ray imaging is to obtain the image quality requiredfor a given detection task, while ensuring that the patient dose is kept as lowas reasonably achievable. The two most common strategies for dose reductionare: optimizing incident x-ray beams and utilizing energy informationof transmitted beams with new detector techniques (spectral imaging). Inthis thesis, dose optimization schemes were investigated in two x-ray imagingsystems: digital mammography and computed tomography (CT).

In digital mammography, the usefulness of anti-scatter grids was investigatedas a function of breast thickness with varying geometries and experimentalconditions. The general conclusion is that keeping the grid is optimalfor breasts thicker than 5 cm, whereas the dose can be reduced without a gridfor thinner breasts.

A photon-counting silicon-strip detector developed for spectral mammographywas characterized using synchrotron radiation. Energy resolution, ΔE/Ein, was measured to vary between 0.11-0.23 in the energy range 15-40 keV, which is better than the energy resolution of 0.12-0.35 measured inthe state-of-the-art photon-counting mammography system. Pulse pileup hasshown little effect on energy resolution.

In CT, the performance of a segmented silicon-strip detector developedfor spectral CT was evaluated and a theoretical comparison was made withthe state-of-the-art CT detector for some clinically relevant imaging tasks.The results indicate that the proposed photon-counting silicon CT detector issuperior to the state-of-the-art CT detector, especially for high-contrast andhigh-resolution imaging tasks.

The beam quality was optimized for the proposed photon-counting spectralCT detector in two head imaging cases: non-enhanced imaging and Kedgeimaging. For non-enhanced imaging, a 120-kVp spectrum filtered by 2half value layer (HVL) copper (Z = 29) provides the best performance. Wheniodine is used in K-edge imaging, the optimal filter is 2 HVL iodine (Z = 53)and the optimal kVps are 60-75 kVp. In the case of gadolinium imaging, theradiation dose can be minimized at 120 kVp filtered by 2 HVL thulium (Z =69).

Ort, förlag, år, upplaga, sidor
STOCKHOLM: KTH Royal Institute of Technology, 2016. s. viii, 73
Serie
TRITA-FYS, ISSN 0280-316X ; 0280-316X
Nyckelord
mammography, anti-scatter grid, photon-counting, spectral computed tomography, silicon strip, ASIC, energy resolution, Compton scatter, material decomposition, K-edge imaging
Nationell ämneskategori
Medicinteknik
Forskningsämne
Medicinsk teknologi
Identifikatorer
urn:nbn:se:kth:diva-184092 (URN)978-91-7595-919-1 (ISBN)
Disputation
2016-04-22, FA 31, ROSLAGSTULLSBACKEN 21, KTH, STOCKHOLM, 09:00 (Engelska)
Opponent
Handledare
Anmärkning

QC 20160401

Tillgänglig från: 2016-04-01 Skapad: 2016-03-23 Senast uppdaterad: 2022-06-23Bibliografiskt granskad

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Chen, HanCederström, BjörnXu, ChengPersson, MatsDanielsson, Mats

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Chen, HanCederström, BjörnXu, ChengPersson, MatsKarlsson, StaffanDanielsson, Mats
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Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment
Radiologi och bildbehandling

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