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A Disposable Chip Enabling Metering In Dried Blood Spot Sampling
KTH, School of Electrical Engineering (EES), Micro and Nanosystems.
Karolinska University Hospital. (Deptartment of Laboratory Medicine)
KTH, School of Electrical Engineering (EES), Micro and Nanosystems.ORCID iD: 0000-0001-9552-4234
Karolinska University Hospital. (Department of Medicine, Division of Clinical Pharmacology)
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2013 (English)Conference paper, Poster (with or without abstract) (Refereed)
Abstract [en]

This work presents a disposable chip for metering and transferring an exactly defined liquid volume into a paper matrix by capillary filling and emptying of a microchannel together with self-actuated dissolvable valves. Once a liquid droplet of 20-50 μl is applied to the chip, a volume of 1 μl is automatically metered, separated from the applied volume and subsequently transferred into conventional Whatman 903 paper used in Dried Blood Spot (DBS) sampling. The presented concept allows accurate volume metering for lateral flow devices and is here designed to the specific purpose of metering blood spots for DBS analysis. The material costs for each chip are below 0.04 €.

Place, publisher, year, edition, pages
2013. p. 281-283
Keywords [en]
Dried Blood Spot, DBS, Metering, Dissolvable Valving
National Category
Other Medical Engineering
Research subject
Medical Technology
Identifiers
URN: urn:nbn:se:kth:diva-146631Scopus ID: 2-s2.0-84907319693ISBN: 9781632666246 (print)OAI: oai:DiVA.org:kth-146631DiVA, id: diva2:724292
Conference
Micro TAS 2013
Note

QC 20140613

Available from: 2014-06-12 Created: 2014-06-12 Last updated: 2024-03-18Bibliographically approved

Open Access in DiVA

proceeding_microTAS 2013(2655 kB)383 downloads
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File name FULLTEXT01.pdfFile size 2655 kBChecksum SHA-512
64609cd6835a8534c24be18f7b5b3ffcfd6bd9d51fe846f3ffb53423eddd26665def2e46f2ae6995f7eef77d16f34ea3a760e8c9160fb8dde869bae4f15d369d
Type fulltextMimetype application/pdf

Scopus

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Lenk, GabrielStemme, GöranRoxhed, Niclas

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Total: 383 downloads
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CiteExportLink to record
Permanent link

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Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf