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A Molecular Motor
KTH, School of Engineering Sciences (SCI).
2016 (English)Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
Abstract [en]

Molecular motors are enzymes which are used as cargo transporters in cells. In this report

the motor protein kinesin is studied. The kinetics of the kinesin molecule are described.

Models for the mechanism in which the chemical energy in the form of ATP is transformed

into mechanical work are discussed. The motion of one of the two cooperarting kinesin

heads is simulated. The head is modelled as a Brownian particle subject to a periodic,

time-dependent potential, which models the energy landscape experienced by the kinesin

head during different states of the stepping cycle. The dependence of the speed and

efficiency of the molecular motor on different load forces is investigated. The actual

relevance of the model used in the simulation is also discussed.

Place, publisher, year, edition, pages
2016. , 16 p.
National Category
Engineering and Technology
URN: urn:nbn:se:kth:diva-193630OAI: diva2:1033261
Available from: 2016-10-06 Created: 2016-10-06 Last updated: 2016-10-06Bibliographically approved

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