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Capillary density: An important parameter in nailfold capillaroscopy
Medical Image and Signal Processing Research Center, Isfahan University of Medical Sciences, Isfahan, Iran. (Nailfold capillaroscopy images)
KTH, School of Technology and Health (STH). (Nailfold capillaroscopy images)ORCID iD: 0000-0001-7320-2306
Department of Rheumatology, Alzahra Hospital, Isfahan University of Medical Sciences, Isfahan, Iran. (Nailfold capillaroscopy images)
Medical Image and Signal Processing Research Center, Isfahan University of Medical Sciences, Isfahan, Iran. (Nailfold capillaroscopy images)
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2017 (English)In: Microvascular Research, ISSN 0026-2862, E-ISSN 1095-9319, Vol. 109, 7-18 p.Article in journal, Editorial material (Refereed) Published
Abstract [en]

Nailfold capillaroscopy is one of the various noninvasive bioengineering methods used to investigate skin microcirculation. It is an effective examination for assessing microvascular changes in the peripheral circulation; hence it has a significant role for the diagnosis of Systemic sclerosis with the classic changes of giant capillaries as well as the decline in capillary density with capillary dropout. The decline in capillary density is one of microangiopathic features existing in connective tissue disease. It is detectable with nailfold capillaroscopy. This parameter is assessed by applying quantitative measurement. In this article, we reviewed a common method for calculating the capillary density and the relation between the number of capillaries as well as the existence of digital ulcers, pulmonary arterial hypertension, autoantibodies, scleroderma patterns and different scoring system.

Place, publisher, year, edition, pages
Stockholm: Elsevier, 2017. Vol. 109, 7-18 p.
Keyword [en]
Nailfold capillaroscopy; Capillary density; Antinuclear antibodies; Digital ulcer; Pulmonary arterial hypertension
National Category
Medical and Health Sciences
Research subject
Medical Technology
Identifiers
URN: urn:nbn:se:kth:diva-193699DOI: 10.1016/j.mvr.2016.09.001Scopus ID: 2-s2.0-84988851167OAI: oai:DiVA.org:kth-193699DiVA: diva2:1033733
Note

QC 20161017

Available from: 2016-10-09 Created: 2016-10-09 Last updated: 2017-11-30Bibliographically approved

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