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Computational studies of DNA sequencing with solid-state nanopores: Key issues and future prospects
KTH, School of Biotechnology (BIO), Theoretical Chemistry and Biology. Zhejiang Univ, Peoples R China.
KTH, School of Biotechnology (BIO), Theoretical Chemistry and Biology.ORCID iD: 0000-0002-1763-9383
KTH, School of Biotechnology (BIO), Theoretical Chemistry and Biology.ORCID iD: 0000-0001-8198-9284
2014 (English)In: Frontiers in Chemistry, E-ISSN 2296-2646, Vol. 2, no FEB, 5Article in journal (Refereed) Published
Abstract [en]

Owing to the potential use for real personalized genome sequencing, DNA sequencing with solid-state nanopores has been investigated intensively in recent time. However, the area still confronts problems and challenges. In this work, we present a brief overview of computational studies of key issues in DNA sequencing with solid-state nanopores by addressing the progress made in the last few years. We also highlight future challenges and prospects for DNA sequencing using this technology.

Place, publisher, year, edition, pages
Frontiers Media S. A , 2014. Vol. 2, no FEB, 5
Keyword [en]
Bio-nanotechnology, Computer modeling, DNA sequencing, Graphene nanopore, Molecular simulation, Solid-state nanopore, Theory
National Category
Biological Sciences
Identifiers
URN: urn:nbn:se:kth:diva-195337DOI: 10.3389/fchem.2014.00005ISI: 000209678600008Scopus ID: 2-s2.0-84987641951OAI: oai:DiVA.org:kth-195337DiVA: diva2:1044851
Note

QC 20161107

Available from: 2016-11-07 Created: 2016-11-02 Last updated: 2016-11-07Bibliographically approved

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