Simple and environmentally friendly fabrication of superhydrophobic alkyl ketene dimer coated MALDI concentration plates
2017 (English)In: Journal of the American Society for Mass Spectrometry, ISSN 1044-0305, E-ISSN 1879-1123Article in journal (Refereed) Published
Here we present a method to manufacture peptide-concentrating MALDI-plates with alkyl ketene dimer (AKD) as a new superhydrophobic coating. The fabrication of the hydrophobic plates included application of AKD by airbrush, and negative contact printing to generate the concentration sites. Deposited sample droplets were contained within the prestructured sites, and self-adjusted onto the site if slightly misplaced. No AKD contamination was observed, and the plates could easily be cleaned and regenerated. The S/N values for four model peptides was about twice as high compared with a standard steel plate and a commercial concentration plate.
Place, publisher, year, edition, pages
MALDI Concentration plates Alkyl ketene dimer
IdentifiersURN: urn:nbn:se:kth:diva-204944DOI: 10.1007/s13361-017-1657-4OAI: oai:DiVA.org:kth-204944DiVA: diva2:1087090
QC 201704192017-04-052017-04-052017-04-19Bibliographically approved