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Microbubble assisted cell sorting by acoustophoresis
KTH, School of Biotechnology (BIO). KTH, Centres, Science for Life Laboratory, SciLifeLab.
KTH, School of Biotechnology (BIO).
KTH, School of Biotechnology (BIO). KTH, School of Engineering Sciences (SCI), Applied Physics.
KTH, School of Technology and Health (STH), Medical Engineering, Medical Imaging.ORCID iD: 0000-0002-3699-396X
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2016 (English)In: 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016, Chemical and Biological Microsystems Society , 2016, p. 1677-1678Conference paper, Published paper (Refereed)
Abstract [en]

Polymer shelled gas microbubbles (MBs) are used to sort cells in a microfluidic chip under acoustic standing waves (SW). When particles are subjected to SW based on their acoustic contrast factor (ACF) they migrate to nodes (positive contrast factor particles; PACP) or antinodes (negative acoustic contrast particles; NACP)[1]. We have bounded functionalized MBs with cells such that, they can be selectively migrated to antinodes under SW and sorted from unbounded cell both in no flow and flow conditions. Here we demonstrate acoustic mediated microbubble tagged cell sorting with 75% efficiency.

Place, publisher, year, edition, pages
Chemical and Biological Microsystems Society , 2016. p. 1677-1678
National Category
Medical Biotechnology
Identifiers
URN: urn:nbn:se:kth:diva-207568Scopus ID: 2-s2.0-85014178442ISBN: 9780979806490 (print)OAI: oai:DiVA.org:kth-207568DiVA, id: diva2:1102707
Conference
20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016, 9 October 2016 through 13 October 2016
Note

Conference code: 126047; Export Date: 22 May 2017; Conference Paper; Correspondence Address: Faridi, M.A.; School of Biotechnology, Royal Institute of Technology KTHSweden; email: mafaridi@kth.se. QC 20170530

Available from: 2017-05-30 Created: 2017-05-30 Last updated: 2017-05-30Bibliographically approved

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Grishenkov, DmitryWiklund, MartinRussom, Aman

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Faridi, M. A.Ramachandraiah, H.Iranmanesh, I. S.Grishenkov, DmitryWiklund, MartinRussom, Aman
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School of Biotechnology (BIO)Science for Life Laboratory, SciLifeLabApplied PhysicsMedical ImagingProteomics and Nanobiotechnology
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