Development of a solid-phase extraction method for simultaneous extraction of adipic acid, succinic acid and 1,4-butanediol formed during hydrolysis of poly(butylene adipate) and poly(butylene succinate
2004 (English)In: Journal of Chromatography A, ISSN 0021-9673, E-ISSN 1873-3778, Vol. 1022, no 1-2, 171-177 p.Article in journal (Refereed) Published
A solid-phase extraction (SPE) method was developed for the simultaneous extraction of dicarboxylic acids and diols formed during hydrolysis of poly(butylene succinate), PBS, and poly(butylene adipate), PBA. Four commercial non-polar SPE columns, three silica based: C-8, C-18, C-18 (EC), and one resin based: ENV+, were tested for the extraction of succinic acid, adipic acid and 1,4-butanediol, the expected final hydrolysis products of PBS and PBA. ENV+ resin was chosen as a solid-phase, because it displayed the best extraction efficiency for 1,4-butanediol and succinic acid. Linear range for the extracted analytes was 1-500 ng/mul for adipic acid and 2-500 ng/mul for 1,4-butanediol and succinic acid. Detection and quantification limits for the analytes were between 1-2 and 2-7 ng/mul, respectively, and relative standard deviations were between 3 and 7%. Good repeatability and low detection limits made the developed SPE method and subsequent gas chromatography-mass spectrometry (GC-MS) analysis a sensitive tool for identification and quantification of hydrolysis products at early stages of degradation.
Place, publisher, year, edition, pages
2004. Vol. 1022, no 1-2, 171-177 p.
Adipic acid; Butanediol; Organic acids; Poly(butylene adipate); Poly(butylene succinate); Succinic acid; Hydrolysis; Mass spectrometry; Organic acids; Polybutenes; Silica; Solid phase extraction (SPE); Gas chromatography; 1, 4 butanediol; adipic acid; adipic acid derivative; poly(butylene adipate); poly(butylene succinate); succinic acid; succinic acid derivative; unclassified drug; analytic method; article; gas chromatography; hydrolysis; mass spectrometry; priority journal; productivity; quantitative analysis; solid phase extraction; Adipic Acids; Butylene Glycols; Gas Chromatography-Mass Spectrometry; Hydrolysis; Molecular Weight; Polymers; Sensitivity and Specificity; Succinic Acid
Polymer Chemistry Polymer Technologies
IdentifiersURN: urn:nbn:se:kth:diva-6754DOI: 10.1016/j.chroma.2003.09.036ISI: 000187662700020PubMedID: 14753784ScopusID: 2-s2.0-0242573152OAI: oai:DiVA.org:kth-6754DiVA: diva2:11555
QC 201008052007-02-142007-02-142016-05-30Bibliographically approved