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The biomechanical rupture risk assessment of abdominal aortic aneurysms—method and clinical relevance
KTH, School of Engineering Sciences (SCI), Solid Mechanics (Dept.).
2018 (English)In: Lecture Notes in Applied and Computational Mechanics, Springer Verlag , 2018, p. 233-253Conference paper, Published paper (Refereed)
Abstract [en]

An Abdominal Aortic Aneurysm (AAA) is an enlargement of the infrarenal aorta, a serious condition whose clinical treatment requires assessing its risk of rupture. This chapter reviews the current state of the Biomechanical Rupture Risk Assessment (BRRA), a non-invasive diagnostic method to calculate such AAA rupture risk, and emphasizes on constitutive modeling of AAA tissues. Histology and mechanical properties of the normal and aneurysmatic walls are summarized and related to proposed constitutive descriptions. Models for the passive vessel wall as well as their adaptation in time are discussed. Reported clinical BRRA validation studies are summarized and their clinical relevance is discussed. Despite open problems in AAA biomechanics, like robust modeling vascular tissue adaptation to mechanical and biochemical environments, a significant body of current validation evidence suggests integrating the BRRA method into the clinical decision-making process. 

Place, publisher, year, edition, pages
Springer Verlag , 2018. p. 233-253
Keywords [en]
Biomechanics, Blood vessels, Decision making, Histology, Noninvasive medical procedures, Tissue, Abdominal aortic aneurysms, Clinical decision making, Clinical treatments, Infrarenal aorta, Non-invasive diagnostics, Robust modeling, Validation study, Vascular tissue, Risk assessment
National Category
Civil Engineering
Identifiers
URN: urn:nbn:se:kth:diva-216816DOI: 10.1007/978-3-319-59548-1_13Scopus ID: 2-s2.0-85028949372OAI: oai:DiVA.org:kth-216816DiVA, id: diva2:1162825
Note

Export Date: 24 October 2017; Book Chapter; Correspondence Address: Gasser, T.C.; KTH Royal Institute of TechnologySweden; email: gasser@kth.se. QC 20171205

Available from: 2017-12-05 Created: 2017-12-05 Last updated: 2018-01-16Bibliographically approved

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Gasser, T. Christian

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CiteExportLink to record
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Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
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  • de-DE
  • en-GB
  • en-US
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  • nn-NB
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  • Other locale
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Output format
  • html
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  • asciidoc
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