Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
On-a-chip Biosensing Based on All-Dielectric Nanoresonators
Barcelona Institute of Science and Technology, Spain.ORCID iD: 0000-0002-4437-6291
Show others and affiliations
2017 (English)In: Nano letters (Print), ISSN 1530-6984, E-ISSN 1530-6992, Vol. 17, no 7, 4421-4426 p.Article in journal (Refereed) Published
Abstract [en]

Nanophotonics has become a key enabling technology in biomedicine with great promises in early diagnosis and less invasive therapies. In this context, the unique capability of plasmonic noble metal nanoparticles to concentrate light on the nanometer scale has widely contributed to biosensing and enhanced spectroscopy. Recently, high-refractive index dielectric nanostructures featuring low loss resonances have been proposed as a promising alternative to nanoplasmonics, potentially offering better sensing performances along with full compatibility with the microelectronics industry. In this letter we report the fitst demonstration of biosensing with silicon nanoresonators integrated in state-of-the-art microfluidics. Our lab-on-a-chip platform enables detecting Prostate Specific Antigen (PSA) cancer marker in human serum with a sensitivity that meefs clinical needs. These performances are directly compared with its plasmonic counterpart based on gold nanorods. Our work opens new opportunities in the development of future point-of-care devices toward a more personalized healthcare.

Place, publisher, year, edition, pages
American Chemical Society (ACS), 2017. Vol. 17, no 7, 4421-4426 p.
Keyword [en]
Lab-on-chip, all-dielectric nanoresonators, biosensing cancer, silicon
National Category
Atom and Molecular Physics and Optics Nano Technology
Identifiers
URN: urn:nbn:se:kth:diva-219930DOI: 10.1021/acs.nanolett.7b01518ISI: 000405643300060PubMedID: 28616986Scopus ID: 2-s2.0-85024382253OAI: oai:DiVA.org:kth-219930DiVA: diva2:1165995
Funder
EU, FP7, Seventh Framework Programme, 64790Swedish Research Council, 637-2014-6894
Note

QC 20171214

Available from: 2017-12-14 Created: 2017-12-14 Last updated: 2017-12-14Bibliographically approved

Open Access in DiVA

No full text

Other links

Publisher's full textPubMedScopus

Search in DiVA

By author/editor
Svedendahl, Mikael
In the same journal
Nano letters (Print)
Atom and Molecular Physics and OpticsNano Technology

Search outside of DiVA

GoogleGoogle Scholar

doi
pubmed
urn-nbn

Altmetric score

doi
pubmed
urn-nbn
Total: 2 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf