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Influence of ligand-receptor interactions on force-extension behavior within the freely jointed chain model
KTH, School of Chemical Science and Engineering (CHE).
2017 (English)In: Physical review. E, ISSN 2470-0045, E-ISSN 2470-0053, Vol. 96, no 6, article id 062501Article in journal (Refereed) Published
Abstract [en]

We study the influence of receptor-ligand interactions on the force response of single polymer chains theoretically. The extension of the chain is modeled in terms of freely jointed chain or elastic freely jointed chain (EFJC) models. The situation involving noninteracting bonds is solved exactly, while effects of interactions are treated within a mean-field approximation. The form with shorter bonds governs the low force situation, while the form with longer bonds is relevant in the high force regime. We further discuss the accuracy of approximate relations, which were used to describe the response of the EFJC model.

Place, publisher, year, edition, pages
American Physical Society, 2017. Vol. 96, no 6, article id 062501
National Category
Physical Sciences
Identifiers
URN: urn:nbn:se:kth:diva-220456DOI: 10.1103/PhysRevE.96.062501ISI: 000417491500003Scopus ID: 2-s2.0-85038125220OAI: oai:DiVA.org:kth-220456DiVA, id: diva2:1170452
Note

QC 20180103

Available from: 2018-01-03 Created: 2018-01-03 Last updated: 2018-01-03Bibliographically approved

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Radiom, Milad
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