Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Strain and strain rate generated by shear wave elastography in an ex vivo porcine aorta
KTH, School of Technology and Health (STH), Medical Engineering.ORCID iD: 0000-0002-9654-447X
KTH, School of Technology and Health (STH), Medical Engineering. Karolinska Institutet, Sverige.ORCID iD: 0000-0003-1002-2070
Show others and affiliations
2017 (English)In: 2017 IEEE International Ultrasonics Symposium (IUS), IEEE Computer Society, 2017, article id 8091581Conference paper (Refereed)
Abstract [en]

In order to generate trackable shear waves in soft tissues, transmitted pulses in shear wave elastography (SWE) are longer than conventional clinical ultrasound pulses. Nevertheless, they typically obey mechanical and thermal regulatory limits. In arterial applications, specific safety concerns may arise, as acoustic radiation (ARF)-induced stresses and strain rates could potentially affect the arterial wall. The aim of this study was to assess ARF-induced strain and strain rates in ex vivo arteries. A porcine aorta (diameters 8.5 mm, wall thickness 1.2 mm) was pressurized by a saline-filled water column at 60 and 120 mmHg. A Verasonics V1 system and a L7-4 transducer were used to generate the ARF in the middle of the anterior wall (F-number = 1, push length = [100, 200, 300] μs) and to perform plane-wave imaging (10 kHz). Cumulative axial displacement was estimated using 2D auto-correlation. The axial strain rate was calculated as the time-derivative of the axial strain, obtained by spatial linear regression of the displacement inside the anterior wall. The ex vivo peak strain and strain rate were compared with peak strain and strain rate values induced by the blood pressure changes in two healthy individuals and two patients with coronary artery disease at rest and measured by a dedicated in house speckle tracking algorithm. ARF-induced ex vivo peak strains were in the range 0.3-1% and strain rates in the range 6-23 s-1. Peak values were more affected by longer push duration than pressurization level. In vivo physiological peak strain was 33% and strain rate was 2 s-1. ARF-induced strain rates in vivo are likely to be lower than those assessed in this ex vivo setup due to ultrasound attenuation and the effect of surrounding tissue. Therefore, the results of the performed study suggest that SWE could be used in a safe manner for arterial applications even though specific effects of high strain rates are to be explored.

Place, publisher, year, edition, pages
IEEE Computer Society, 2017. article id 8091581
Series
IEEE International Ultrasonics Symposium, IUS, ISSN 1948-5719
Keywords [en]
Acoustic radiation force, Artery, Safety, Shear wave elastography, Strain, Strain rate
National Category
Radiology, Nuclear Medicine and Medical Imaging
Identifiers
URN: urn:nbn:se:kth:diva-220744DOI: 10.1109/ULTSYM.2017.8091581ISI: 000416948400025Scopus ID: 2-s2.0-85039434244ISBN: 9781538633830 OAI: oai:DiVA.org:kth-220744DiVA, id: diva2:1170921
Conference
2017 IEEE International Ultrasonics Symposium, IUS 2017, Washington, United States, 6 September 2017 through 9 September 2017
Funder
Swedish Research Council, 2015-04237
Note

QC 20180105

Available from: 2018-01-05 Created: 2018-01-05 Last updated: 2018-01-12Bibliographically approved

Open Access in DiVA

No full text in DiVA

Other links

Publisher's full textScopus

Authority records BETA

Maksuti, EliraLarsson, DavidLarsson, Matilda

Search in DiVA

By author/editor
Maksuti, EliraLarsson, DavidLarsson, Matilda
By organisation
Medical Engineering
Radiology, Nuclear Medicine and Medical Imaging

Search outside of DiVA

GoogleGoogle Scholar

doi
isbn
urn-nbn

Altmetric score

doi
isbn
urn-nbn
Total: 11 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf