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Advances in nanotechnology for cancer biomarkers
KTH. Alexandria University, Egypt.
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2018 (English)In: Nano Today, ISSN 1748-0132, E-ISSN 1878-044X, Vol. 18, p. 103-123Article in journal (Refereed) Published
Abstract [en]

Cancer biomarkers with high selectivity, specificity and reproducibility play essential role in diagnosis, prognosis and prediction of treatment efficacy in cancer patients. However, the current biomarker assays used in clinics could be improved due to low sensitivity and specificity. Nanoparticle-based assays are emerging as an upcoming approach, providing ultra-high sensitivity and specificity in cancer biomarker detection. The current survey presents an overview of strategies used in the development and integration of nanoparticles for cancer biomarker detection, including mass spectrometry, optical and electrical detection methods. Moreover, we discuss the future trends in the field in correlation to new approaches from fundamental and practical standpoints.

Place, publisher, year, edition, pages
Elsevier, 2018. Vol. 18, p. 103-123
Keyword [en]
Nanoparticle, Cancer biomarker, Targeting, Mass spectrometry detection, Optical detection, Electrical detection
National Category
Cancer and Oncology
Identifiers
URN: urn:nbn:se:kth:diva-225086DOI: 10.1016/j.nantod.2017.12.008ISI: 000427101900012Scopus ID: 2-s2.0-85041628487OAI: oai:DiVA.org:kth-225086DiVA, id: diva2:1193955
Funder
The Cancer Research Funds of Radiumhemmet, 161082
Note

QC 20180328

Available from: 2018-03-28 Created: 2018-03-28 Last updated: 2018-03-28Bibliographically approved

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Muhammed, Mamoun

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