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Sensing Spindle Neurons in the Insula with Multi-shell Diffusion MRI
Parietal, Inria, Paris, France.
KTH, School of Electrical Engineering and Computer Science (EECS).ORCID iD: 0000-0002-3213-0040
Athena, Inria, Sophia-Antipolis, France.
DEFI, Inria, Palaiseau, France.
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2018 (English)Conference paper, Published paper (Refereed)
Abstract [en]

Sensing microstructural characteristics of human brain tissue with clinical scanners has been an area of heated debate in the diffusion MRI (dMRI) community. In this work, we propose that diffusion MRI on clinical scanners is sensitive to the presence of spindle neurons.

Spindle neurons, located in the insular and anterior cingular cortices, are only present in mammals with high cognitive functions. Albeit this neurons' role is not yet known, evidence suggests they facilitate rapid long-range information integration.

In this work, we provide theoretical and in-silico evidence that the dMRI signal is sensitive to the presence of spindle neurons as well as preliminary evidence on human dMRI images. 

Place, publisher, year, edition, pages
France: ISMRM-ESMRMB 2018 , 2018.
National Category
Natural Sciences
Research subject
Applied and Computational Mathematics; Applied Medical Technology
Identifiers
URN: urn:nbn:se:kth:diva-225130OAI: oai:DiVA.org:kth-225130DiVA, id: diva2:1194283
Conference
Annual Meeting ISMRM-ESMRMB, June 16-21 2018, Paris, France
Note

QC 20180523

Available from: 2018-03-29 Created: 2018-03-29 Last updated: 2018-05-23Bibliographically approved

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Nguyen, Van Dang

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