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Electrospinning of Hybrid Nanofibres Elaborated with PEG Core Dendrimers and SPIONs Synthesized in-situ: as Multifunctional Material for Biomedical Applications
KTH, School of Chemical Science and Engineering (CHE).
2017 (English)In: PROCEEDINGS OF THE 2017 IEEE 7TH INTERNATIONAL CONFERENCE NANOMATERIALS: APPLICATION & PROPERTIES (NAP) / [ed] Pogrebnjak, AD Novosad, V Zukowski, P Protsenko, SI Shabelnyk, Y, IEEE , 2017, article id UNSP 03NNSA37Conference paper, Published paper (Refereed)
Abstract [en]

Nanoparticles have emerged as a major attraction for preparation of novel materials with unique properties. They are usually a combination of extraordinary materials not found in nature. Expanding on that concept, nanofibres with additional components for biomedical applications were fabricated. Magnetic nanoparticles were chosen because they exhibit super paramagnetic properties for a wide range of applications in biomedicine. These particles were coated with polymer PEG 2000, which allowed bond formation of bond between the positive end of the dipole in SPIONs and the anion in PEG 2000, thus providing stability for use for a few weeks after preparation and further helping the interaction with PEG dendrimers and PEO. A colloid of SPIONs with PEG dendrimers and PEO was then used for electrospinning, providing multifunctional nanofibres of SPIONs characteristic rust-colour. The average diameter depended on the generation of dendrimers used in the colloid, ranging from 113 nm to 123 nm. The fibres were further characterized for thermal stability using TGA. The nanofibres proved a higher thermal stability, which is one of the many functionalities obtained by consisting of diverse, nanoparticle components. This can lead to numerous possibilities that could be fabricated by building on this methodology. For example, hybrid materials containing pioneering combinations can be developed.

Place, publisher, year, edition, pages
IEEE , 2017. article id UNSP 03NNSA37
Series
Proceedings of the international conference Nanomaterials-Applications and properties, ISSN 2306-580X
Keyword [en]
electrospinning, hybrid material, organo-metallic, biomedical, polymer nanofibres, nanoparticles, dendrimers, characterization
National Category
Chemical Engineering
Identifiers
URN: urn:nbn:se:kth:diva-225276ISI: 000426973100123ISBN: 978-1-5386-2810-2 OAI: oai:DiVA.org:kth-225276DiVA, id: diva2:1194421
Conference
7th IEEE International Conference Nanomaterials - Application and Properties (NAP), SEP 10-15, 2017, Odessa, UKRAINE
Note

QC 20180403

Available from: 2018-04-03 Created: 2018-04-03 Last updated: 2018-04-03Bibliographically approved

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CiteExportLink to record
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