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Large-scale brain simulation and disorders of consciousness. Mapping technical and conceptual issues
KTH, Centres, Science for Life Laboratory, SciLifeLab. Karolinska Inst, Dept Neurosci, Solna, Sweden.
2018 (English)In: Frontiers in Psychology, ISSN 1664-1078, E-ISSN 1664-1078, Vol. 9, no April, article id 585Article in journal (Refereed) Published
Abstract [en]

Modeling and simulations have gained a leading position in contemporary attempts to describe, explain, and quantitatively predict the human brain's operations. Computer models are highly sophisticated tools developed to achieve an integrated knowledge of the brain with the aim of overcoming the actual fragmentation resulting from different neuroscientific approaches. In this paper we investigate the plausibility of simulation technologies for emulation of consciousness and the potential clinical impact of large-scale brain simulation on the assessment and care of disorders of consciousness (DOCs), e.g., Coma, Vegetative State/Unresponsive Wakefulness Syndrome, Minimally Conscious State. Notwithstanding their technical limitations, we suggest that simulation technologies may offer new solutions to old practical problems, particularly in clinical contexts. We take DOCs as an illustrative case, arguing that the simulation of neural correlates of consciousness is potentially useful for improving treatments of patients with DOCs.

Place, publisher, year, edition, pages
Frontiers Media S.A., 2018. Vol. 9, no April, article id 585
Keywords [en]
Brain modeling, Brain simulation, Consciousness, Consciousness disorders, Neuroethics
National Category
Psychology
Identifiers
URN: urn:nbn:se:kth:diva-227600DOI: 10.3389/fpsyg.2018.00585ISI: 000430833800001Scopus ID: 2-s2.0-85045916466OAI: oai:DiVA.org:kth-227600DiVA, id: diva2:1204959
Funder
EU, Horizon 2020, 720270Science for Life Laboratory - a national resource center for high-throughput molecular bioscience
Note

QC 20180509

Available from: 2018-05-09 Created: 2018-05-09 Last updated: 2018-05-14Bibliographically approved

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Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
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Output format
  • html
  • text
  • asciidoc
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