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Microneedle-based system for minimally invasive continuous monitoring of glucose in the dermal interstitial fluid
KTH.
KTH.
2018 (English)In: 2018 IEEE Micro Electro Mechanical Systems (MEMS), Institute of Electrical and Electronics Engineers (IEEE), 2018, Vol. 2018, p. 408-411Conference paper, Published paper (Refereed)
Abstract [en]

We present a minimally invasive continuous glucose monitoring (CGM) device. The system consists in an ultra-miniaturized electrochemical sensor probe (70 × 700 × 50 μm3) inserted into the lumen of a hollow silicon microneedle. The implantable portion of the system is 50-fold smaller than state-of-the-art commercial products, thus enabling glucose monitoring in the dermis and a less invasive insertion procedure. Passive interstitial fluid extraction is achieved, making the daily use of this system practically viable. Moreover, the sensor positioning provides minimal delay in tracking glycaemia (5-10 minutes lag), due to the minimal distance between sensing electrodes and microneedle opening. The demonstrated system has therefore the potential to enable minimally invasive, fast and reliable CGM in patients affected by diabetes.

Place, publisher, year, edition, pages
Institute of Electrical and Electronics Engineers (IEEE), 2018. Vol. 2018, p. 408-411
Series
Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS), ISSN 1084-6999
National Category
Embedded Systems
Identifiers
URN: urn:nbn:se:kth:diva-228550DOI: 10.1109/MEMSYS.2018.8346574Scopus ID: 2-s2.0-85046998695ISBN: 9781538647820 OAI: oai:DiVA.org:kth-228550DiVA, id: diva2:1210368
Conference
31st IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2018, Belfast, United Kingdom, 21 January 2018 through 25 January 2018
Funder
VINNOVA, E!8573EU, European Research Council, 267528
Note

QC 20180528

Available from: 2018-05-28 Created: 2018-05-28 Last updated: 2018-05-28Bibliographically approved

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Stemme, GöranRoxhed, Niclas

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CiteExportLink to record
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Citation style
  • apa
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  • ieee
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  • de-DE
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  • Other locale
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Output format
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