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Long-term health-related quality of life, survival and costs by different levels of functional outcome six months after stroke
Karolinska Inst, Dept Clin Neurosci, Div Neurol, Tomtebodavagen 18A,Floor 5, S-17177 Stockholm, Sweden..
Oslo Univ Hosp, Dept Internal Med & Cardiol, Oslo, Norway.;Univ Tromso, Inst Clin Med, Tromso, Norway..
Quantify Res, Stockholm, Sweden.;Karolinska Inst, Dept Neurobiol Care Sci & Soc, Stockholm, Sweden..
KTH, School of Architecture and the Built Environment (ABE), Centres, Centre for Traffic Research, CTR. KTH Royal Inst Technol, Ctr Safety Res, Stockholm, Sweden..ORCID iD: 0000-0001-7606-8771
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2018 (English)In: European Stroke Journal, ISSN 2396-9873, E-ISSN 2396-9881, Vol. 3, no 2, p. 157-164Article in journal (Refereed) Published
Abstract [en]

Introduction: Information about the impact of functional outcome after stroke is currently missing on health-related quality of life, survival and costs. This information would be valuable for health economic evaluations and for allocation of resources in stroke health care. Patients and methods: Data on 297 Swedish patients included in the Third International Stroke Trial were analysed including functional outcome at six months (measured by Oxford Handicap Scale), health-related quality of life up to 18 months (EQ-5D-3L) and survival up to 36 months. We used record linkage to collect data on costs up to 36 months, using national patient registers. Results: Patients with a better functional outcome level at six months had a significantly better health-related quality of life at 18 months (p<0.05), better long-term survival (p<0.05) and lower costs (p<0.001), for all time points up to 36 months. The difference in costs was mainly due to differences in days spent in hospital (p<0.005). Discussion: This study showed an association between functional outcome at six months and health-related quality of life up to 18 months, and costs up to 36 months. Conclusion: Functional outcome six months after stroke is an important determinant of health-related quality of life, survival and costs over 36 months. Effective interventions aimed at reducing short-term disability levels are therefore also expected to reduce the overall burden of stroke.

Place, publisher, year, edition, pages
SAGE PUBLICATIONS LTD , 2018. Vol. 3, no 2, p. 157-164
Keywords [en]
Stroke, quality adjusted life year, health economy, EQ-5D, functional level, survival
National Category
Health Care Service and Management, Health Policy and Services and Health Economy
Identifiers
URN: urn:nbn:se:kth:diva-228418DOI: 10.1177/2396987317753444ISI: 000432064200008OAI: oai:DiVA.org:kth-228418DiVA, id: diva2:1210466
Note

QC 20180528

Available from: 2018-05-28 Created: 2018-05-28 Last updated: 2018-05-28Bibliographically approved

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