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Review on Life Cycle of Parabens, Synthesis, Degradation, Characterization and Safety Analysis
Imperial Coll London, Dept Chem Engn, London, England..
KTH, School of Chemical Science and Engineering (CHE), Chemical Engineering and Technology.ORCID iD: 0000-0001-5180-9895
UCL, Dept Chem Engn, London, England..
2018 (English)In: Current organic chemistry, ISSN 1385-2728, E-ISSN 1875-5348, Vol. 22, no 8, p. 769-779Article, review/survey (Refereed) Published
Abstract [en]

In this review, we show the life cycle of parabens, commonly used preservatives that exist in nature and commercial products. Typical synthetic methods to produce parabens, and a set of complimentary characterization techniques to monitor the composition of parabens are also highlighted. This includes solid state analysis using Scanning Electron Microscope (SEM), Differential Scanning Calorimetry (DSC) and X-Ray Diffraction (XRD), in-situ monitoring of crystallization process using Focused Beam Reflectance Measurement (FBRM), Particle Vision Measurement (PVM), quantitative detection via High Performance Liquid Chromatography (HPLC), and Gas Chromatography (GC). An improved understanding of the overall physical, biophysical and chemical properties of parabens and their life cycle, summarized in this article, are vital for the safety control and extensive applications of relevant products in food, cosmetic and pharmaceutical industries.

Place, publisher, year, edition, pages
Bentham Science Publicing , 2018. Vol. 22, no 8, p. 769-779
Keywords [en]
Paraben, synthesis, degradation, characterization, safety, analysis
National Category
Materials Chemistry
Identifiers
URN: urn:nbn:se:kth:diva-230558DOI: 10.1174/1385171811666180113150313ISI: 000432914800005Scopus ID: 000432914800005OAI: oai:DiVA.org:kth-230558DiVA, id: diva2:1220106
Note

C 20180618

Available from: 2018-06-18 Created: 2018-06-18 Last updated: 2018-06-18Bibliographically approved

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