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Polymeric Nanoparticles Explored for Drug-Delivery Applications
KTH, School of Chemical Science and Engineering (CHE), Fibre and Polymer Technology.ORCID iD: 0000-0001-8887-9141
KTH, School of Chemical Science and Engineering (CHE), Fibre and Polymer Technology.ORCID iD: 0000-0002-8348-2273
2018 (English)In: Gels and Other Soft Amorphous Solids, American Chemical Society (ACS), 2018, p. 315-331Chapter in book (Refereed)
Abstract [en]

The main drawback of conventional chemotherapeutics is their non-specific distribution in the body which causes serious side effects to healthy cells. As a consequence, the drug concentration reaching the tumor is reduced, resulting in suboptimal therapeutic efficacy. The discovery that polymer-based nanomaterials can be used for controlled drug delivery systems offers well-defined reservoirs for a wide spectrum of pharmaceutical agents, with the ability to reduce the toxic response. The most widely explored polymeric nanocarriers, including biodegradable polymers, amphiphilic copolymers and polymers that form unimolecular micelles, are discussed in this brief chapter.

Place, publisher, year, edition, pages
American Chemical Society (ACS), 2018. p. 315-331
Series
ACS Symposium Series, ISSN 0097-6156 ; 1296
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Other Chemistry Topics
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URN: urn:nbn:se:kth:diva-238379DOI: 10.1021/bk-2018-1296.ch016Scopus ID: 2-s2.0-85052665835ISBN: 9780841233164 (print)OAI: oai:DiVA.org:kth-238379DiVA, id: diva2:1264895
Note

QC 20181121

Available from: 2018-11-21 Created: 2018-11-21 Last updated: 2018-11-21Bibliographically approved

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Asem, HebaMalmström, Eva

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