Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Soft-Tissue Imaging in a Human Mummy: Propagation-based Phase-Contrast CT
KTH, School of Engineering Sciences (SCI), Applied Physics, Biomedical and X-ray Physics. KTH, School of Biotechnology (BIO), Centres, Albanova VinnExcellence Center for Protein Technology, ProNova.
KTH, School of Biotechnology (BIO), Centres, Albanova VinnExcellence Center for Protein Technology, ProNova. KTH, School of Engineering Sciences (SCI), Applied Physics, Biomedical and X-ray Physics.
Hosp Varberg, Dept Orthopaed, Varberg, Sweden..
Museum Mediterranean & Near Eastern Antiqu, Stockholm, Sweden..
Show others and affiliations
2018 (English)In: Radiology, ISSN 0033-8419, E-ISSN 1527-1315, Vol. 289, no 3, p. 670-676Article in journal (Refereed) Published
Abstract [en]

Purpose: To evaluate phase-contrast CT as a noninvasive alternative to histology in the study of ancient soft tissue. Materials and Methods: The imaging was performed between May 8 and June 13, 2017. A mummified human hand from ancient Egypt was imaged in a laboratory phase-contrast CT arrangement with propagation-based imaging. The experimental arrangement for propagation-based imaging included a microfocus x-ray source, a rotation stage for the sample, and an x-ray detector. The mummified hand was imaged in two different modes. First, a CT scan of the whole hand was performed in an overview arrangement. Then, a detailed scan of the tip of the middle finger was performed. With imaging distances tailored fora large magnification and to maximize die phase-contrast signal, the estimated resolution in the final images was 6-9 mu m. Results: The overview CT allowed identification tendons of the hand, as well as identification of arteries and nerves in the dehydrated soft tissue. In the detailed phase-contrast setting, virtual histology of the soft tissues of the fingertip could be performed. Blood vessels in the nail bed and the microanatomy of the bone marrow and hypodermis were imaged, and the layers of the skin could be distinguished. Round structures in the adipose tissue were identified as the reamins of adipocytes. Conclusion: Laboratory phase-contrast CT enables imaging of the anatomy and microanatomy of mummified soft tissue with sub-10-mu m resolution and may serve as a complement or alternative to the classic invasive histrologic methods used in soft-tissue paleopathology. (C) RSNA.2018

Place, publisher, year, edition, pages
RADIOLOGICAL SOC NORTH AMERICA , 2018. Vol. 289, no 3, p. 670-676
National Category
Physical Sciences
Identifiers
URN: urn:nbn:se:kth:diva-239987DOI: 10.1148/radiol.2018180945ISI: 000450569200015PubMedID: 30251933Scopus ID: 2-s2.0-85056714548OAI: oai:DiVA.org:kth-239987DiVA, id: diva2:1269656
Funder
Swedish Research CouncilWallenberg Foundations
Note

QC 20181211

Available from: 2018-12-11 Created: 2018-12-11 Last updated: 2018-12-11Bibliographically approved

Open Access in DiVA

No full text in DiVA

Other links

Publisher's full textPubMedScopus

Authority records BETA

Romell, JennyHertz, Hans

Search in DiVA

By author/editor
Romell, JennyVagberg, WilliamHertz, Hans
By organisation
Biomedical and X-ray PhysicsAlbanova VinnExcellence Center for Protein Technology, ProNova
In the same journal
Radiology
Physical Sciences

Search outside of DiVA

GoogleGoogle Scholar

doi
pubmed
urn-nbn

Altmetric score

doi
pubmed
urn-nbn
Total: 39 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf