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High throughput trapping and arrangement of biological cells using self-assembled optical tweezer
South China Normal Univ, South China Acad Adv Optoelect, Ctr Opt & Electromagnet Res, Guangzhou 510006, Guangdong, Peoples R China.;Tongren Univ, Sch Mat & Chem Engn, Tongren 554300, Guizhou, Peoples R China..
South China Normal Univ, South China Acad Adv Optoelect, Ctr Opt & Electromagnet Res, Guangzhou 510006, Guangdong, Peoples R China..
South China Normal Univ, South China Acad Adv Optoelect, Ctr Opt & Electromagnet Res, Guangzhou 510006, Guangdong, Peoples R China..
South China Normal Univ, South China Acad Adv Optoelect, Ctr Opt & Electromagnet Res, Guangzhou 510006, Guangdong, Peoples R China..
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2018 (English)In: Optics Express, ISSN 1094-4087, E-ISSN 1094-4087, Vol. 26, no 26, p. 34665-34674Article in journal (Refereed) Published
Abstract [en]

Lately, a fiber-based optical tweezer that traps and arranges the micro/nanoparticles is crucial in practical applications, because such a device can trap the biological samples and drive them to the designated position in a microfluidic system or vessel without harming them. Here, we report a new type of fiber optical tweezer, which can trap and arrange erythrocytes. It is prepared by coating graphene on the cross section of a microfiber. Our results demonstrate that thermal-gradient-induced natural convection flow and thermophoresis can trap the erythrocytes under low incident power, and the optical scattering force can arrange them precisely under higher incident power. The proposed optical tweezer has high flexibility, easy fabrication, and high integration with lab-on-a-chip, and shows considerable potential for application in various fields, such as biophysics, biochemistry, and life sciences.

Place, publisher, year, edition, pages
OPTICAL SOC AMER , 2018. Vol. 26, no 26, p. 34665-34674
National Category
Atom and Molecular Physics and Optics
Identifiers
URN: urn:nbn:se:kth:diva-241201DOI: 10.1364/OE.26.034665ISI: 000454149000101Scopus ID: 2-s2.0-85059218640OAI: oai:DiVA.org:kth-241201DiVA, id: diva2:1280415
Note

QC 20190118

Available from: 2019-01-18 Created: 2019-01-18 Last updated: 2019-01-18Bibliographically approved

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He, Sailing

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