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In vivo experiments to characterize the mechanical behavior of the human uterine cervix
Swiss Fed Inst Technol, Dept Mech Engn, Zurich, Switzerland..
Swiss Fed Inst Technol, Dept Mech Engn, Zurich, Switzerland..
Med Unit, Dept Obstet & Gynaecol, Graz, Austria..
Med Unit, Dept Obstet & Gynaecol, Graz, Austria..
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2006 (English)In: MECHANICS OF BIOLOGICAL TISSUE / [ed] Holzapfel, GA Ogden, RW, SPRINGER-VERLAG BERLIN , 2006, p. 431-+Conference paper, Published paper (Refereed)
Abstract [en]

Experimental results of in vivo measurements for characterizing the mechanical behavior of human uterine cervices are documented. Aspiration experiments were performed in, vivo, before vaginal/abdominal hysterectomy, and ex vivo, approximately 1.5 hours after extraction. We defined various parameters to characterize the mechanical response from the aspiration experiments. The reproducibility of the mechanical data from the in vivo aspiration experiments has been analyzed. The in vivo and ex vivo mechanical responses of uterine cervices did not differ considerably: the ex vivo situation shows a stronger history, dependence in tissue pre-conditioning, whereas the differences in the time dependence of the mechanical response were not significant. This study represents a first step of a clinical application aiming at characterizing the mechanical response of normal cervical tissue at different gestational ages, and to identify the mechanical parameters that characterize pathologic conditions such as cervical insufficiency leading to preterm delivery.

Place, publisher, year, edition, pages
SPRINGER-VERLAG BERLIN , 2006. p. 431-+
National Category
Medical Engineering
Identifiers
URN: urn:nbn:se:kth:diva-242438DOI: 10.1007/3-540-31184-X_31ISI: 000237286900031OAI: oai:DiVA.org:kth-242438DiVA, id: diva2:1287436
Conference
IUTAM Symposium on Mechanics of Biological Tissue
Note

QC 20190211

Available from: 2019-02-11 Created: 2019-02-11 Last updated: 2019-02-11Bibliographically approved

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CiteExportLink to record
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