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IMI - Clinical Myopia Control Trials and Instrumentation Report
Aston Univ, Ophthalm Res Grp, Birmingham, W Midlands, England..ORCID iD: 0000-0003-4673-8927
Indiana Univ, Sch Optometry, Bloomington, IN USA..
Univ Houston, Coll Optometry, Ocular Surface Inst, Houston, TX USA..
Queensland Univ Technol, Sch Optometry & Vis Sci, Inst Hlth & Biomed Innovat, Brisbane, Qld, Australia..
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2019 (English)In: Investigative Ophthalmology and Visual Science, ISSN 0146-0404, E-ISSN 1552-5783, Vol. 60, no 3, p. M132-M160Article in journal (Refereed) Published
Abstract [en]

The evidence-basis based on existing myopia control trials along with the supporting academic literature were reviewed; this informed recommendations on the outcomes suggested from clinical trials aimed at slowing myopia progression to show the effectiveness of treatments and the impact on patients. These outcomes were classified as primary (refractive error and/or axial length), secondary (patient reported outcomes and treatment compliance), and exploratory (peripheral refraction, accommodative changes, ocular alignment, pupil size, outdoor activity/lighting levels, anterior and posterior segment imaging, and tissue biomechanics). The currently available instrumentation, which the literature has shown to best achieve the primary and secondary outcomes, was reviewed and critiqued. Issues relating to study design and patient selection were also identified. These findings and consensus from the International Myopia Institute members led to final recommendations to inform future instrumentation development and to guide clinical trial protocols.

Place, publisher, year, edition, pages
ASSOC RESEARCH VISION OPHTHALMOLOGY INC , 2019. Vol. 60, no 3, p. M132-M160
Keywords [en]
myopia control, myopia progression, clinical trial guidelines, instrumentation, recommendations
National Category
Ophthalmology
Identifiers
URN: urn:nbn:se:kth:diva-246277DOI: 10.1167/iovs.18-25955ISI: 000460128100007PubMedID: 30817830OAI: oai:DiVA.org:kth-246277DiVA, id: diva2:1298957
Note

QC 20190325

Available from: 2019-03-25 Created: 2019-03-25 Last updated: 2019-03-25Bibliographically approved

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Lundström, Linda

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