Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Alternative Separation Methods: Flocculation and Precipitation
KTH.
2018 (English)In: Biopharmaceutical Processing: Development, Design, and Implementation of Manufacturing Processes, Elsevier , 2018, p. 221-239Chapter in book (Other academic)
Abstract [en]

The most common alternative separation methods used in bioprocessing are flocculation and precipitation. They are proven, readily scaled, do not require overt energy input or capital investment, and can offer significant selectivity. They have the ability to handle modern challenges such as high-density feeds that tax the limits of industry "workhorse" methods such as centrifugation, filtration, and chromatography. They appear particularly well suited to be used in the initial stages of bioprocessing, either in target-capture or contaminant-removal. Such methods are compatible with modern high-throughput screening of operating conditions, as well as single-use equipment for use in batch or continuous processes. This chapter provides more insight into a discussion of flocculation and precipitation, initiated in the preceding chapter.

Place, publisher, year, edition, pages
Elsevier , 2018. p. 221-239
Keywords [en]
Alternative separation, Bioprocess, Clarification, Extraction, Flocculation, Precipitation, Purification and separation
National Category
Biological Sciences
Identifiers
URN: urn:nbn:se:kth:diva-247228DOI: 10.1016/B978-0-08-100623-8.00011-6Scopus ID: 2-s2.0-85054354936ISBN: 9780128125526 (print)ISBN: 9780081006238 (print)OAI: oai:DiVA.org:kth-247228DiVA, id: diva2:1301645
Note

QC 20190402

Available from: 2019-04-02 Created: 2019-04-02 Last updated: 2019-04-02Bibliographically approved

Open Access in DiVA

No full text in DiVA

Other links

Publisher's full textScopus

Search in DiVA

By author/editor
Van Alstine, J. M.
By organisation
KTH
Biological Sciences

Search outside of DiVA

GoogleGoogle Scholar

doi
isbn
urn-nbn

Altmetric score

doi
isbn
urn-nbn
Total: 14 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf