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Nanometre-sized droplets from a gas dynamic virtual nozzle
Uppsala Univ, Dept Cell & Mol Biol, Lab Mol Biophys, Husargatan 3,Box 596, SE-75124 Uppsala, Sweden. .
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2019 (English)In: Journal of applied crystallography, ISSN 0021-8898, E-ISSN 1600-5767, Vol. 52, p. 800-808Article in journal (Refereed) Published
Abstract [en]

This paper reports on improved techniques to create and characterize nometre-sized droplets from dilute aqueous solutions by using a gas namic virtual nozzle (GDVN). It describes a method to measure the size stribution of uncharged droplets, using an environmental scanning ectron microscope, and provides theoretical models for the droplet zes created. The results show that droplet sizes can be tuned by justing the gas and liquid flow rates in the GDVN, and at the lowest quid flow rates, the size of the water droplets peaks at about 120nm. is droplet size is similar to droplet sizes produced by electrospray nization but requires neither electrolytes nor charging of the lution. The results presented here identify a new operational regime r GDVNs and show that predictable droplet sizes, comparable to those tained by electrospray ionization, can be produced by purely chanical means in GDVNs.

Place, publisher, year, edition, pages
International Union of Crystallography , 2019. Vol. 52, p. 800-808
Keywords [en]
aerosols, droplet size, gas dynamic virtual nozzles (GDVNs), environmental scanning electron microscopy, coherent X-ray diffractive imaging (CXDI), single particles, sample delivery, structural biology, nanoscience
National Category
Other Engineering and Technologies
Identifiers
URN: urn:nbn:se:kth:diva-255734DOI: 10.1107/S1600576719008318ISI: 000477717400013Scopus ID: 2-s2.0-85069956136OAI: oai:DiVA.org:kth-255734DiVA, id: diva2:1342459
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QC 20190813

Available from: 2019-08-13 Created: 2019-08-13 Last updated: 2019-10-04Bibliographically approved

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