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A multi-step least-squares method for nonlinear rational models
KTH, School of Electrical Engineering and Computer Science (EECS), Automatic Control. (Centre for Advanced Bioproduction)
KTH, School of Electrical Engineering and Computer Science (EECS), Automatic Control. (Centre for Advanced Bioproduction)
KTH, School of Engineering Sciences in Chemistry, Biotechnology and Health (CBH), Industrial Biotechnology. (Cell Technology Group; Centre for Advanced Bioproduction)ORCID iD: 0000-0002-5370-4621
KTH, School of Electrical Engineering and Computer Science (EECS), Automatic Control. (Centre for Advanced Bioproduction)ORCID iD: 0000-0002-9368-3079
2019 (English)In: Proceedings of the American Control Conference, Institute of Electrical and Electronics Engineers (IEEE), 2019, p. 4509-4514, article id 8814404Conference paper, Published paper (Refereed)
Abstract [en]

Models rational in the parameters arise frequently in biosystems and other applications. As with all models that are non-linear in the parameters, direct parameter estimation, using e.g. nonlinear least-squares, can become challenging due to the issues of local minima and finding good initial estimates. Here we propose a multi-step least-squares method for a class of nonlinear rational models. The proposed method is applied to an extended Monod-type model. Numerical simulations indicate that the proposed method is consistent.

Place, publisher, year, edition, pages
Institute of Electrical and Electronics Engineers (IEEE), 2019. p. 4509-4514, article id 8814404
Series
Proceedings of the American Control Conference, ISSN 0743-1619
National Category
Other Electrical Engineering, Electronic Engineering, Information Engineering
Identifiers
URN: urn:nbn:se:kth:diva-262599Scopus ID: 2-s2.0-85072268828ISBN: 9781538679265 (print)OAI: oai:DiVA.org:kth-262599DiVA, id: diva2:1366172
Conference
2019 American Control Conference, ACC 2019; Philadelphia; United States; 10 July 2019 through 12 July 2019
Note

QC 20191028

Available from: 2019-10-28 Created: 2019-10-28 Last updated: 2019-10-28Bibliographically approved

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Jacobsen, Elling W.Chotteau, VéroniqueHjalmarsson, Håkan

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