Nitration of 2-substituted pyrimidine-4,6-diones, structure and reactivity of 5,5-gem-dinitropyrimidine-4,6-diones
2002 (English)In: Journal of Organic Chemistry, ISSN 0022-3263, E-ISSN 1520-6904, Vol. 67, no 22, 7833-7838 p.Article in journal (Refereed) Published
Nitration of some 2-substituted pyrimidine-4,6-diones in sulfuric acid was studied, which afforded previously unknown 5,5-gem-dinitropyrimidine-4,6-diones in high yields. The gem-dinitro products were easily attacked by nucleophiles with concomitant formation of gem-dinitroacetyl derivatives, which in turn could be further hydrolyzed to salts of dinitromethane and triureas.
Place, publisher, year, edition, pages
2002. Vol. 67, no 22, 7833-7838 p.
Hydrolysis, Methane, Molecular structure, Nitration, Substitution reactions, Sulfuric acid, Urea
IdentifiersURN: urn:nbn:se:kth:diva-9034DOI: 10.1021/jo025952xISI: 000178820200035PubMedID: 12398510OAI: oai:DiVA.org:kth-9034DiVA: diva2:14574
Tidigare titel: Nitration of 2-Substituted Pyrimidine-4,6-diones, Structure and Reactivity of 5,5-gem-Dinitropyrimidine
QC 201009072006-01-262006-01-262010-09-07Bibliographically approved